IRCT201107317164N1 IRCT 2011-08-10 Golestan medical Sciences university, Vice chancellor for research Effect of charcoal on uremic pruritus Comparison of the effects of Oral charcoal capsule with Aluminum Hydroxide Syrup on pruritus in hemodialytic patients in Gorgan 5th – Azar hospital. 2007-06-12 anticipated 30 Complete https://irct.ir/trial/7602 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Crossover, Purpose: Treatment. 2-3 Renal failure. Intervention 1: In the second group, subjects receive Aluminum Hydroxide syrup (30 cc; three times per day before each meal), for two weeks. Wash out period is 48 hours. In the second period treatment for tow weeks, use oral activated Charcoal capsule 6gr daily in three doses. Intervention 2: In the first group, Subjects receive oral activated Charcoal capsule 6gr daily in three doses, for two weeks. Wash out period is 48 hours. second period treatment (tow weeks), continue by Aluminum Hydroxide syrup (30 cc; three times per day before each meal).