<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20240316061312N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2024-04-04</date_registration>
      <primary_sponsor>The University of Faisalabad</primary_sponsor>
      <public_title>Carpal Tunnel Syndrome, Neural Tensioner Technique and Neural Slider Technique in Pregnant Women</public_title>
      <acronym></acronym>
      <scientific_title>Comparative Effects of Neural slider technique and Neural Tensioner technique on wrist pain, function , and grip strength in pregnant women with Carpal Tunnel Syndrome</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2024-02-17</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>59</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/76141</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: non-probability consecutive sampling, Blinding description: single blinded study was conducted to minimize the chance of biaseness, this study was used to allocate the members in single groups. this description involve concealing details that could bias accessors when evaluating retrieval systems or algorithm. this ensures fair and unbiased evaluation of system's performance.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Carpal tunnel syndrome.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: Nerve tensioner neurodynamic technique In order to effectively address the affected distal extremity, we will carefully position it in six distinct and precise orientations. Begin by positioning subject wrist in a neutral position, ensuring your fingers and thumb are fully flexed. Next, will extend fingers and thumb completely. Will gradually introduce wrist extension. Follow this by extending your thumb as well. Maintain a supinated forearm position. Finally, gently apply a slight tension to thumb. Frequency: 5-10 repetitions for 3-5 sessions a day. Each position to be maintained for 5-7 seconds. The tensioner intervention was conducted in two sets, each lasting 5 minutes, with a 1-minute rest period between sets. Intervention 2: Intervention group: Nerve slider neurodynamic technique The nerve slider neurodynamic approach used in this investigation followed the sequence of shoulder girdle depression, glenohumeral abduction and lateral rotation, supination of the forearm, and extension of the wrist, thumb, and fingers. The individual will perform alternating dynamic movements of elbow flexion and wrist extension in this posture, followed by alternating movements of elbow extension and wrist flexion. The therapist varied the sequence of motions based on the level of resistance in the tissues. The speed and magnitude of the movement were modified to ensure that the procedure did not cause any discomfort. The slider intervention was conducted in two sets, each lasting 5 minutes, with a 1-minute rest period between sets, with frequency of 10 repetition.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
comparative effects of neural slider technique and neural tensioner technique on wrist pain, function, and grip strength in pregnant women with carpal tunnel syndrome

When:
15 days after publication

To whom:
Google scholar

Conditions:
Access to the data will be facilitated through a specified mechanism, such as a secure online portal or data sharing platform. Requests for access will be reviewed by a designated committee or entity responsible for ensuring that they meet the established criteria and comply with relevant regulations and guidelines. Additional supporting information and documents may be provided to assist requesters in understanding the available data and its potential applications.

Where to obtain:
The University of Faisalabad
 38000
 https://tuf.edu.pk/
 00924187509715

How to obtain:
To receive the documents or data files, the process typically involves the following steps: 1. Request Initiation: The applicant submits a formal request specifying the documents or data files they need. 2. Verification and Authorization: The organization verifies the request and ensures that the applicant is authorized to access the requested documents or data files. This may involve confirming the identity of the requester and checking their permissions. 3. Processing Time: The processing time varies depending on the complexity of the request, the volume of documents or data files, and any legal or regulatory requirements. It could range from a few hours to several weeks. 4. Document Retrieval or Data Extraction: Once the request is approved, the organization retrieves the documents from their archives or extracts the requested data from their databases. 5. Quality Assurance: Before releasing the documents or data files to the applicant, the organization may conduct quality checks to ensure accuracy and completeness. 6. Delivery: The documents or data files are delivered to the applicant through a secure channel, such as encrypted email, secure file transfer protocols, or a secure online portal. 7. Confirmation of Receipt: The applicant acknowledges receipt of the documents or data files, confirming that they have received the information they requested.

Comments:
</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Dr. Zainab Boota;PT</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Faisal Town, West Canal Road, Faisalabad, Punjab</address>
        <city>Faisalabad</city>
        <country1>Pakistan</country1>
        <zip>38000</zip>
        <telephone>+92 335 7916317</telephone>
        <email>Zainboota9698@gmail.com</email>
        <affiliation>The University of Faisalabad</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Dr. Gulraiz Ayub; PT</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Faisal Town, West Canal Road, Faisalabad, Punjab</address>
        <city>Faisalabad</city>
        <country1>Pakistan</country1>
        <zip>38000</zip>
        <telephone>+92 317 0075508</telephone>
        <email>Gulraizayub70@gmail.com</email>
        <affiliation>The University of Faisalabad</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Pakistan</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Age 22-35 years
Unilateral CTS
females in third trimester of pregnancy
Discomfort, tingling, or sensations of paraesthesia in the thumb, the index, the middle, and the radial half of ring finger
VAS score (24-hour maximum pain): 4–7 cm at 10 cm VAS scale
Positive Tinel’s sign
Positive Phalen’s test
Sleep disruption from hand pain
Signed informed consent</inclusion_criteria>
      <agemin>22 years</agemin>
      <agemax>35 years</agemax>
      <gender>Female</gender>
      <exclusion_criteria>Undergone any form of conservative treatment within the last month
Prior neurovascular surgery within the last six months pertaining to the same area of the body
Neurovascular pathologic conditions affecting the same area of the body other than CTS
Systemic pathologies associated with CTS, such as hypothyroidism, rheumatoid arthritis, or diabetes mellitus
Chronic pain conditions, such as myofascial pain syndrome or fibromyalgia which can manifest as hand-referred pain
CTS as a result of a fracture of the upper extremity or trauma to the median nerve
Undergone previous surgery for CTS
Exhibit severe thenar muscle atrophy
Psychosocial problems</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: Nerve tensioner neurodynamic technique In order to effectively address the affected distal extremity, we will carefully position it in six distinct and precise orientations. Begin by positioning subject wrist in a neutral position, ensuring your fingers and thumb are fully flexed. Next, will extend fingers and thumb completely. Will gradually introduce wrist extension. Follow this by extending your thumb as well. Maintain a supinated forearm position. Finally, gently apply a slight tension to thumb. Frequency: 5-10 repetitions for 3-5 sessions a day. Each position to be maintained for 5-7 seconds. The tensioner intervention was conducted in two sets, each lasting 5 minutes, with a 1-minute rest period between sets.</i_keyword>
      <i_keyword>Intervention group: Nerve slider neurodynamic technique The nerve slider neurodynamic approach used in this investigation followed the sequence of shoulder girdle depression, glenohumeral abduction and lateral rotation, supination of the forearm, and extension of the wrist, thumb, and fingers. The individual will perform alternating dynamic movements of elbow flexion and wrist extension in this posture, followed by alternating movements of elbow extension and wrist flexion. The therapist varied the sequence of motions based on the level of resistance in the tissues. The speed and magnitude of the movement were modified to ensure that the procedure did not cause any discomfort. The slider intervention was conducted in two sets, each lasting 5 minutes, with a 1-minute rest period between sets, with frequency of 10 repetition.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Wrist Pain. Timepoint: before intervention and 3 weeks after intervention. Method of measurement: Visual Analogue Scale.</prim_outcome>
      <prim_outcome>Functional status. Timepoint: before intervention and 3 weeks after intervention. Method of measurement: Boston Carpal Tunnel Questionnaire (BCTQ).</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Grip strength. Timepoint: before intervention and 3 weeks after intervention. Method of measurement: Hand-held dynamometer.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>The University of Faisalabad</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2024-01-05</approval_date>
        <contact_name>Research and Ethics / technical committee for the university of Faisalabad</contact_name>
        <contact_address>Faisal Town, West Canal Road, Faisalabad, Punjab Faisalabad Punjab Pakistan</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
