IRCT20240409061460N1 IRCT 2024-04-22 Ahvaz University of Medical Sciences Comparison of bladder botox and tamsulosin tablets in the treatment of symptomatic benign prostatic hyperplasia (BPH) patients. Comparison of the effect of intravesical injection of Botox with oral tamsulosin 0.4 mg in the treatment of lower urinary tract symptom disorders (LUTS) in patients with symptomatic benign prostatic hyperplasia (BPH). 2024-05-21 anticipated 40 Complete https://irct.ir/trial/76422 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Random allocation is done by block method. 5 blocks of 8 are used. In this way, the number of 5 blocks of 8 will be randomly extracted using WIN PEPI software. 8 compounds will be from two groups A (injection group) and group B (oral pill group). N/A Benign prostatic hyperplasia. Intervention 1: Intervention group: Patients in this group will be injected with Botox in the bladder neck area.The way to inject Botox is that every 100 international units of Bo-A will be diluted in 2 ml of NT saline. The injection dose will be determined according to the prostate volume. For prostate volume less than 30 cc, between 30 and 60 cc and more than 60 cc, respectively, 100, 200 and 300 international units of BoNT-A under spinal anesthesia in the operation room will be injected in the neck area of ​​the bladder. Intervention 2: Control group: Patients in this group will be treated with tamsulosin 0.4 mg orally once a day. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information.