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IRCT20240429061587N1 IRCT 2024-07-19 Tabriz University of Medical Sciences Evaluation of Zataria multiflora and Propolis mouthwash effect on Streptococcus mutans and Lactobacillus in saliva and dental biofilm Evaluation of Zataria multiflora and Propolis mouthwash effect on Streptococcus mutans and Lactobacillus in saliva and dental biofilm 2024-05-09 anticipated 150 Complete https://irct.ir/trial/76488 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: The method of random allocation of people will be the method of random blocks of 4. After collecting the volunteers to participate in the study, by using random allocation online sites and entering the data of the individuals, the allocation of the volunteers to each of the studied groups will be done, Blinding description: The blinding process for the participants will be done by similarization: propolis, Shirazi thyme, propolis + Shirazi thyme and chlorhexidine mouthwashes prepared in black containers without labels will be used for the participants, so that the participants Do not know the type of material used. The prepared samples will also be sent to the microbiologist in coded form without knowing the intervention group or gold standard. Finally, the samples will be sent to the laboratory for microbial culture evaluation and analysis. 2-3 Tooth decay-causing microorganisms in saliva and teeth biofilm. Intervention 1: Prescribing propolis mouthwash. Intervention 2: Intervention group: Prescribing Zataria Multiflora mouthwash. Intervention 3: Intervention group: Prescribing propolis + Zataria Multiflora mouthwash. Intervention 4: Intervention group: Prescribing CHX mouthwash(gold standard). Intervention 5: Control group: Prescribing distilled water. Yes - There is a plan to make this available What will be shared: The mentioned items will be provided When: one year To whom: researchers Conditions: university demand Where to obtain: Baqiyatallah University of Medical Science How to obtain: ... Comments:
public Dara Fazlzade
Hoseini Al , Payam Ave , Elgoli Sq
Tabriz Iran (Islamic Republic of) 51688436 +98 914 613 1428 fazlzade@gmail.com Bagheiat-allah University of Medical Sciences scientific Dara Fazlzade
Hoseini Al , Payam Ave , Elgoli Sq
Tabriz Iran (Islamic Republic of) 51688643 +98 914 613 1428 fazlzade@gmail.com Bagheiat-allah University of Medical Sciences Iran (Islamic Republic of) 18 year old volunteers without systemic conditions without active oral cavity disease such as caries or periodontal disease able to stop oral hygiene maintenance for one day without using fixed or removable orthodontic appliance or removable partial denture 18 years no limit Both Having an underlying disease or an active disease in the oral cavity Use of fixed or removable orthodontic appliance or removable prosthesis Unwillingness to participate in the study Being under 18 years of age K02 Dental caries Prevention Prevention Prevention Prevention Placebo Prescribing propolis mouthwash Intervention group: Prescribing Zataria Multiflora mouthwash Intervention group: Prescribing propolis + Zataria Multiflora mouthwash Intervention group: Prescribing CHX mouthwash(gold standard) Control group: Prescribing distilled water The amount of dental caries-causing microorganisms in saliva and dental biofilm. Timepoint: Before and after mouthwash and one week after using mouthwash. Method of measurement: Cultivation and colony counting. Tabriz University of Medical Sciences Approved 2023-12-29 The specialized committee of ethics in biomedical research South Sheikh Bahai St, Mollasadra St,Vanak Square Tehran Tehran Iran (Islamic Republic of)