]>
IRCT20240413061474N2 IRCT 2024-06-22 Shahid Beheshti University of Medical Sciences The effect of aerobic exercises in pulmonary hypertension (PH) patients with chronic obstructive pulmonary disease (COPD) The effect of aerobic exercises on antioxidant indices of pulmonary hypertension (PH) patients with chronic obstructive pulmonary disease (COPD) 2024-07-22 anticipated 126 Complete https://irct.ir/trial/77478 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Other, Randomization description: For randomization, a simple randomization method is used with the help of a table of random numbers. For this purpose, two groups are named A and B. We choose one of the rows of the table of random numbers at will and the numbers of each row will be between 0 and 9. We assign numbers 0-4 to treatment A and numbers 5-9 to treatment B, Blinding description: Clinical evaluations will be performed by blinded evaluators who are unaware of the interventions assigned to the participants. So that each evaluator receives codes for each patient that are related to training groups. Therefore, the type of grouping and the type of intervention cannot be identified by the clinical assessor. 3 Pulmonary hypertension (PH) with chronic obstructive pulmonary disease (COPD). Intervention 1: Intervention group: In the intervention group, COPD patients diagnosed with pulmonary hypertension according to the protocol, perform aerobic exercises including diaphragmatic breathing exercises and lip bud breathing on the bed, as well as stretching exercises and chest expansion for a total of ten minutes. Then the patient goes to the exercise room, and with an intensity equivalent to 60% of the six-minute walking test, they perform aerobic exercise as follows: At first, the patient walks on a treadmill for 5 minutes at a speed of 1 km/h. (warming up), then he exercises for 15 minutes at a speed equal to 60% of the walking test for six minutes (he continues to walk) and in the last 5 minutes he slows down again at a speed of 2 km/h. slow down. After the end of the exercise, stretching exercises for the lower limb muscles are performed on the treadmill for 10 minutes. Intervention 2: Control group: In the control group, COPD patients diagnosed with pulmonary hypertension only perform physical therapy exercises on the bed, including diaphragmatic breathing and lip bud breathing on the bed, as well as stretching exercises and chest expansion for a total of ten minutes. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information
public Seyed Bashir Mirtajani
Masih Daneshvari Hospital, Darabad
Tehran Iran (Islamic Republic of) 1956944413 +98 21 2610 1000 bashirmirtajani67@gmail.com Shahid Beheshti University of Medical Sciences scientific Aboozar Mojibian
Masih Daneshvari Hospital, Darabad
Tehran Iran (Islamic Republic of) 1956944413 +98 21 2610 1000 dr.a.mojibian@gmail.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) Age more than 18 years Diagnosis of PH through echocardiography Pulmonary arterial pressure (PAP) more than 35 Signing the written consent form to participate in the research project 18 years no limit Both The patient's unwillingness to continue participating in the research project, active cancer, or any disorder prohibiting rehabilitation exercises I27.2 Other secondary pulmonary hypertension Rehabilitation Rehabilitation Intervention group: In the intervention group, COPD patients diagnosed with pulmonary hypertension according to the protocol, perform aerobic exercises including diaphragmatic breathing exercises and lip bud breathing on the bed, as well as stretching exercises and chest expansion for a total of ten minutes. Then the patient goes to the exercise room, and with an intensity equivalent to 60% of the six-minute walking test, they perform aerobic exercise as follows: At first, the patient walks on a treadmill for 5 minutes at a speed of 1 km/h. (warming up), then he exercises for 15 minutes at a speed equal to 60% of the walking test for six minutes (he continues to walk) and in the last 5 minutes he slows down again at a speed of 2 km/h. slow down. After the end of the exercise, stretching exercises for the lower limb muscles are performed on the treadmill for 10 minutes. Control group: In the control group, COPD patients diagnosed with pulmonary hypertension only perform physical therapy exercises on the bed, including diaphragmatic breathing and lip bud breathing on the bed, as well as stretching exercises and chest expansion for a total of ten minutes. Test distance of 6 minutes walk. Timepoint: Before and after rehabilitation. Method of measurement: Six minute walk test. Glutathione peroxidase (GPx). Timepoint: Before and after rehabilitation. Method of measurement: Spectrophotometry. Catalase. Timepoint: Before and after rehabilitation. Method of measurement: Spectrophotometry. Total antioxidant capacity. Timepoint: Spectrophotometry. Method of measurement: Before and after rehabilitation. Shahid Beheshti University of Medical Sciences Approved 2024-04-23 Ethics Committee of Tuberculosis and Lung Disease Research Institute of Shahid Beheshti University o Darabad, Masih Daneshvari Hospital Tehran Tehran Iran (Islamic Republic of)