IRCT20250111064355N1 IRCT 2025-02-06 Ahvaz University of Medical Sciences Effect of Dorzolamide on macular thickness after phaco surgery PDME The effect of topical Dorzolamide on macular thickening after phaco surgery in diabetic patients 2025-01-15 anticipated 68 Complete https://irct.ir/trial/81263 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: The assignment of interventions to patients is conducted randomly using permuted block randomization with random block sizes of 4, 6, and 8 (based on a table of random permutations). The randomization list is prepared by a biostatistician. The intervention used in this study is allocated according to the randomized list by an individual not involved in the study and blinded to its objectives, based on corresponding codes enclosed in sealed envelopes, Blinding description: Evaluation of outcomes was performed by a researcher who was blinded about the group assignment. The study protocol and the type of treatment were concealed from our participants. 3 Macular Thickening Following Phacoemulsification Surgery in Diabetic Patients. Intervention 1: Control group: Administering Tearlose artificial tear drops (Sinadarou, Tehran, Iran) every 8 hours, from one day before to 4 weeks after Phaco surgery. Intervention 2: Intervention group: Administering Dorzolamide 2% drops (Dorzamide, Sinadarou, Tehran, Iran) every 8 hours, from one day before to 4 weeks after Phaco surgery. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information available.