IRCT20250111064354N1 IRCT 2025-03-09 Yasouj University of Medical Sciences "Investigating the effect of Eye Movement Desensitization and Reprocessing in Internalized Stigma" EMDR Comparison of the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) on internalized stigma in patients with major depressive disorder. 2025-03-05 anticipated 72 Complete https://irct.ir/trial/81268 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Health service research, Randomization description: Eligible study participants will be randomly assigned to two intervention groups and a control group in blocks of multiples of two (2, 4). This process will be conducted randomly using an online platform called Sealed Envelope. The list of participant allocations to study groups will be extracted through this method based on the total sample size. N/A Internalized stigma. Intervention 1: The intervention group: Eligible study participants will receive eye movement desensitization and reprocessing intervention individually, up to seven sessions depending on individual needs and treatment progress, with a duration of 90 minutes in the first session and 45 minutes in the following sessions, every other day. Intervention 2: The control group: Participants in this group will receive treatment as usual. No - There is not a plan to make this available Justification or reason for not sharing IPD is Patient information and data will be made available to other researchers and writers upon request while maintaining confidentiality and privacy.