IRCT20240815062771N3 IRCT 2025-02-24 Tehran University of Medical Sciences Injection of Plasma Rich in Growth Factor (PRGF) in infertile women with poor ovarian response Evaluation the effect of intraovarian platelet rich plasma activated with calcium gluconate and growth factors injection on infertile women with poor ovarian response and assisted reproductive techniques (ART) outcomes 2025-02-19 anticipated 30 Complete https://irct.ir/trial/81440 interventional Randomization: N/A, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Blinding description: Considering that this therapeutic intervention is interventional, it is not possible to perform blinding for the patient and the treating physician. However, the responsible physician for assessing the outcomes and the analyzing physician are blind. 1-2 poor ovarian response. Intervention 1: Intervention group: PRP extracted from the patient's own blood sample into ovarian cortex. Intervention 2: Intervention group: Injection of activated platelet-rich plasma with calcium gluconate into the ovarian cortex. Intervention 3: Intervention group: Injection of platelet-rich plasma enriched with growth factors into the ovarian cortex (PRGF). Yes - There is a plan to make this available What will be shared: The patients' personal information will be kept completely confidential and only the test results and outcomes will be published. All data obtained in the research will be published in a reputable and relevant scientific journal. When: April 2026 To whom: Researchers working in academic institutions Conditions: The data from this study can be used as an adjuvant treatment in patients with poor ovarian response undergoing IVF/ICSI and will be made available only to researchers and therapists in the medical field. Where to obtain: Mahshad Khodarahmian Email: ma_khodarahmian@gmail.com How to obtain: By sending an email to the correspond author Comments: