IRCT20250325065151N1 IRCT 2025-04-23 Jinnah Postgraduate Medical Center Use of two different local anesthetic drugs Bupivacaine and Tramadol together compared with only using Bupivacaine for post operative pain management Use of Bupivacaine with Tramadol is better than use of only Bupivacaine for post operative pain in Local Anesthesia 2025-04-30 anticipated 100 Complete https://irct.ir/trial/82589 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: A simple randomization method (Lottery method) will be used. Unit of randomization will be individual. Randomization strata in stratified randomization will not be applicable. The tool used will be paper slips drawn randomly from a container. Other tools like a computer software will not be used. The random sequence will be generated by drawing lots (paper slips) from a shuffled container. Allocation concealment will be carried out, Blinding description: In this study, single blinding will be implemented by ensuring that the patients (participants) are unaware of the treatment they received. The patients will be randomly assigned to either the Bupivacaine alone group or the Bupivacaine + Tramadol group using the lottery method. The anesthetic solutions will be prepared in identical syringes to prevent the patients from distinguishing between the two treatments. The patients will not be informed about which anesthetic they received, reducing the risk of reporting bias based on expectations. However, the researchers administering the anesthesia will be aware of the treatment assignments. 3 Postoperative Pain. Intervention 1: Intervention group: patients received 0.5 ml/kg of 0.25% bupivacaine in combination with 1 mg/kg of tramadol. Intervention 2: Control group: patients received 0.5 ml/kg of 0.25% plain bupivacaine only. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Due to institutional policies and ethical considerations regarding patient confidentiality, the deidentified individual participant data (IPD) from this study will not be shared. Additionally, the scope and scale of the study do not necessitate public IPD sharing, and all relevant findings have been adequately presented in the published results.