IRCT20250416065355N1 IRCT 2025-05-14 Zahedan University of Medical Sciences Studying the Electrocardiographic changes in patients with Iron deficiency anemia and minor thalassemia EKG Evaluation of Electrocardiographic Changes in Pateints WithIron Deficiency Anemia and Minor Thalassemia in Ali-Asghar Hospital in Zahedan in 2025 2025-05-22 anticipated 135 Complete https://irct.ir/trial/83000 interventional Randomization: Not randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: This study is a prospective, single-blinded, controlled clinical trial designed to compare hematologic and electrocardiographic (ECG) parameters in children diagnosed with Iron Deficiency Anemia (IDA), Minor Thalassemia, and healthy Controls. A total of 135 children aged 5 to 18 years are enrolled and divided equally into three groups (n = 45 per group). Sampling is conducted using a convenient and accessible method at Ali Asghar Hospital in Zahedan. Participants are allocated to study groups based on their clinical diagnosis. The study is non-randomized; however, investigators responsible for data collection and analysis are blinded to group assignments to reduce assessment bias.Children in the IDA group receive ferrous sulfate at a dose of 5 mg/kg/day for 3 months. Those in the Minor Thalassemia group receive folic acid at a dose of 1 mg/day for 3 months. The Control group receives no pharmacological intervention. Body weight is measured monthly to adjust the dose of ferrous sulfate as needed.All participants follow a similar, age-appropriate, and healthy diet during the study. At the end of the treatment period, ECG parameters are assessed by a pediatric cardiologist who is also one of the study authors, ensuring expert and standardized evaluation, Blinding description: This study is conducted as a single-blinded trial, in which the investigators responsible for data collection and outcome assessment are blinded to group allocation. Although participants and those administering the interventions are aware of the treatment assignments, the investigators analyzing the data do not have access to group information during the evaluation phase. This approach minimizes potential assessment bias and helps ensure the objectivity and validity of the results. 2 Condition 1: Iron deficiency anemia and thalassemia minor. Condition 2: Minor thalassemia. Intervention 1: In Intervention Group 1, children aged 5 to 18 years with iron deficiency anemia were treated with ferrous sulfate. The medication was administered at a daily dose of 5 mg of elemental iron per kilogram of body weight for a duration of 3 months and was given after meals due to potential gastrointestinal side effects. Intervention 2: In Intervention Group 2, children aged 5 to 18 years with minor thalassemia were treated with folic acid. The medication was administered at a daily dose of 1 mg for a duration of 3 months. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.