]>
IRCT20250420065395N1 IRCT 2025-12-13 Ahvaz University of Medical Sciences organic toothpaste Investigating the effect of toothpaste formulation containing pilocarpine loaded in nano mesoporous silica on the salivasecretion rate in people with dry mouth compared to pilocarpine. 2026-04-21 anticipated 30 Complete https://irct.ir/trial/83533 observational Randomization: Not randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive. 3 Dry mouth. Intervention 1: Control group: In this group, people will take the non-medicated toothpaste without knowing they are in the placebo group. They will be examined for saliva samples and questionnaires every 7 days for 2 to 3 months. Intervention 2: Intervention group1: In this group, people will receive toothpaste containing half a percent of the drug and will be examined for saliva samples and questionnaires every 7 days for 2 to 3 months. Intervention 3: Intervention group2: In this group, people will receive toothpaste containing one a percent of the drug and will be examined for saliva samples and questionnaires every 7 days for 2 to 3 months. Yes - There is a plan to make this available What will be shared: All data is potentially shareable after de-identifying individuals. When: Access period starts 12 months after results are published. To whom: The copyright to the information and details must be completely reserved and inaccessible until after the patent is registered. Conditions: No one, except the institution or individual who has obtained the patent and purchased the product, and the individual who owns the idea (Seyedeh Nesa Mousavipour) and the owner of the project (Dr. Eskandar Moghimipour), will have the right to know the results, details, and information of the project. Where to obtain: seyedeh nesa mousavipour, 09167239970 How to obtain: After reviewing the request, a response will be received within 3 to 7 business days. Comments:
public Seyedeh Nesa Mousavipour
Golestan, Esfand Street, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences
Ahvaz Iran (Islamic Republic of) 61357-15794 0989167239970 nesa72.moosavi@gmail.com Ahvaz University of Medical Sciences scientific Seyedeh Nesa Mousavipour
Golestan, Esfand Street, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences
Ahvaz Iran (Islamic Republic of) 61357-15794 0989167239970 nesa72.moosavi@gmail.com Ahvaz University of Medical Sciences Iran (Islamic Republic of) the incidence of mouth dryness is 2 months or more The patient is 20 years old or older. 20 years 60 years Both the criteria for inattention to the study were :to asthma Narrow-angle glaucoma acute iritis allergy to the ingredients of toothpaste pregnancy breastfeeding people who were able to treat their mouths using artificial saliva People who treat their dry mouth using pilocarpine. K11.7 Disturbances of salivary secretion Placebo Treatment - Drugs Treatment - Drugs Control group: In this group, people will take the non-medicated toothpaste without knowing they are in the placebo group. They will be examined for saliva samples and questionnaires every 7 days for 2 to 3 months. Intervention group1: In this group, people will receive toothpaste containing half a percent of the drug and will be examined for saliva samples and questionnaires every 7 days for 2 to 3 months. Intervention group2: In this group, people will receive toothpaste containing one a percent of the drug and will be examined for saliva samples and questionnaires every 7 days for 2 to 3 months. Saliva volume. Timepoint: Once every 7 days for 2 to 3 months. Method of measurement: Questionnaire. Ahvaz University of Medical Sciences Approved 2024-09-29 Ahvaz Jundishapur University of Medical Sciences Golestan, Esfand Street ahvaz Khouzestan Iran (Islamic Republic of)