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IRCT201206237913N2 IRCT 2012-10-08 Emad pharmacy co. Effect of Agicoat(silver nanocrystal dressing) in burn wound Determination of effect of silver nanocrystal dressing (Agicoat) in second degree burn patients of Motahhari hospital and camparision it with Acticoat and silver sulfadiazine 2012-10-22 anticipated 82 Complete https://irct.ir/trial/8356 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Burn. Intervention 1: Dressing with silver sulfadiazine daily (closed dressing): the ointment will apply daily and with sterile gauze will close. Intervention 2: Acticoat dressing apply after wetting it by distilled water and fixing it to bed by tape and melonin and moistuering it by distilled water every 6 hours.The dressing will change every 4 days till wound healing. Intervention 3: Agicoat dressing will undertake after wetting it by distilled water and applying itver wound. The first dressing change will take place after 72 hours or when there is discharge from wound.If there is no discharge the dressing can be left for 7 to 10 days over wound .
public Mohammadrza Akhoondinasab
Motahhari hosp.
Tehran Iran (Islamic Republic of) +98 21 8877 0031 burncenter_89@yahoo.com Tehran University of Medical Sciences scientific Mohammadreza Akhoondinasab
Motahhari hosp.
Tehran Iran (Islamic Republic of) +98 21 8888 4275 akhoondinasab@yahoo.com Tehran University of Medical Sciences Iran (Islamic Republic of) Inclusion criterias : 1- 2nd degree burn between 15- 40% Exclusion criterias : 1- Unresidency of patients in Tehran 2- Underlying medical diseases 3- Sensitivity to Ag 4- Young and old ages: under 5 and over 65 years old 5 years 65 years Both T29.6 Corrosions of multiple regions, no more than second-degree corrosions mentioned Treatment - Drugs Treatment - Drugs Treatment - Drugs Dressing with silver sulfadiazine daily (closed dressing): the ointment will apply daily and with sterile gauze will close Acticoat dressing apply after wetting it by distilled water and fixing it to bed by tape and melonin and moistuering it by distilled water every 6 hours.The dressing will change every 4 days till wound healing Agicoat dressing will undertake after wetting it by distilled water and applying itver wound. The first dressing change will take place after 72 hours or when there is discharge from wound.If there is no discharge the dressing can be left for 7 to 10 days over wound . Scar. Timepoint: 1 mo and 3mo and 6mo after discharge. Method of measurement: Vancover scar scale scor. Wound epithelialization. Timepoint: 1wk after intervention and every 3days till 6wk. Method of measurement: Day. Admission duration. Timepoint: Discharge date. Method of measurement: Discharge date minus admission date. Infection. Timepoint: From time of admission till 1 mo after discharge. Method of measurement: Culture- biopsy. Pain severity. Timepoint: Every 3 days till discharge date. Method of measurement: Visual analogue scale. Expenditure. Timepoint: At discharge date. Method of measurement: Rial. Ethiology. Timepoint: Admission time. Method of measurement: Scald, Fire. Burn percentage. Timepoint: Admission time. Method of measurement: Tatal body surface burned. Age. Timepoint: Admission time. Method of measurement: Year of entrance to study minus birth day. Emad pharmacy co. Approved 2012-08-01 Iranian Registry of Clinical Trial Second floor, No. 7, Poorsina ave., Ghods st., Enghelab square Tehran Iran (Islamic Republic of)