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IRCT138710271555N1 IRCT 2009-02-01 The Filatov Institute of Eye Diseases and Tissue Therapy Excimer laser phototherapeutic keratectomy in treatment of post-burn persistent corneal ulcers Excimer laser phototherapeutic keratectomy vs surgical keratectomy in treatment of post-burn persistent corneal epithelial defects with ulceration 2009-02-01 anticipated 20 Complete https://irct.ir/trial/850 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment, Other design features: In the main group (phototherapeutic keratectomy) all patients, which will fit the inclusion criteria mentioned above, will be included prospectively. In the control group (surgical keratectomy) patients, which will fit the inclusion criteria mentioned above, will be included retrospectively on the basis of case histories analysis. N/A post-burn corneal defect with ulceration. excimer laser phototherapeutic keratectomy.
public Mr Oleksiy Buznyk
Frantsuzkyi bulvar 49/51
Odessa Ukraine 65061 +380482636729 ojogi_glaz@te.net.ua The Filatov Institute of Eye Diseases and Tissue Therapy scientific Mr Oleksiy Buznyk
Frantsuzkyi bulvar 49/51
Odessa Ukraine 65061 +380482636729 ojogi_glaz@te.net.ua The Filatov Institute of Eye Diseases and Tissue Therapy Ukraine Inclusion criteria - presence of post-burn corneal epithelial defect with ulceration, non-decreased size of post-burn corneal defect during 10 days of conventional treatment Exclusion criteria - corneal defect of other than burn etiology, post-burn corneal defect with edge(edges) connected with the limbus and adjacent area of necrosis of perilimbal conjunctiva, deep post-burn corneal ulceration no limit no limit Both H 16.0 Corneal ulcer Other excimer laser phototherapeutic keratectomy Speed of corneal epithelialization. Timepoint: 6 months. Method of measurement: Number of days after operation which was necessary to get corneal epithelialization. Corneal epithelialization it is absence of corneal staining after fluorescein test. Corneal epithelialization rate. Timepoint: 6 months. Method of measurement: Ratio of number of successful corneal epithelializations to number of operations. Visual acuity. Timepoint: 6 months. Method of measurement: Golovin-Sivtsev chart for measurement of visual acuity. Recurrence rate. Timepoint: 6 months. Method of measurement: Ratio of number of corneal defect recurrences to number of successful corneal epithelializations. The Filatov Institute of Eye Diseases and Tissue Therapy Approved 2008-11-07 The Bioethics Committee of the Filatov Institute of Eye Diseases and Tissue Therapy Frantsuzkyi bulvar 49/51 Odessa Ukraine