<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20190727044347N9</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2025-12-05</date_registration>
      <primary_sponsor>Shiraz University of Medical Sciences</primary_sponsor>
      <public_title>Effect of Using Artificial Intelligence in the Flipped Classroom Method on Academic Engagement, Learning Outcomes, and Critical Thinking Disposition in Nursing Students of Fatemeh school of Nursing and Midwifery</public_title>
      <acronym></acronym>
      <scientific_title>Investigating the Effect of Using Artificial Intelligence in the Flipped Classroom Method on Academic Engagement, Learning Outcomes, and Critical Thinking Disposition in Nursing Students of Fatemeh school of Nursing and Midwifery</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2025-12-06</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>54</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/87031</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Education/Guidance, Randomization description: After selecting individuals eligible to participate in the study based on the inclusion criteria, the statistician will use Random Allocation software to randomize the participants into 9 blocks, each block with a size of 6 people, into two experimental and control groups.</study_design>
      <phase>N/A</phase>
      <hc_freetext>.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: the intervention will begin with the introduction and training of artificial intelligence tools, in a non-face-to-face manner and three weeks before the wound training sessions. The training content at this stage includes the introduction of artificial intelligence chatbots and content production tools (introduction to different chatbots, how to access them, how to write prompts, how to produce content such as text and images, PowerPoint and video), which will be presented to students in the form of micro-learning in the form of shortened content with a duration of 3 to 5 minutes as offline educational content in the form of films and written texts on the WhatsApp platform. After selecting the participants, introducing the research and obtaining informed consent in person; the educational topic of wounds and nursing care will be carried out using the flipped classroom method and with content creation by students. The list of educational content of wounds and modern dressings and nursing care will be provided to students as a header to be used to coordinate the content in content creation. The books and articles of the day, which have been approved by the group professors, will be provided to students to use in content production. Students are required to produce content in the form of a video or PowerPoint with audio before the in-person session using artificial intelligence tools and according to the provided list of contents. It should be noted that each group must place individual tasks in content production along with the tools used at the beginning of the content. The content produced is evaluated by the researcher and the best content produced is selected in terms of completeness, novelty, conceptuality, and attractiveness. If necessary, it is edited, corrected, and completed, and the final version is uploaded to the Navid system. Students then answer five related multiple-choice questions individually before the in-person class. These questions will be different from the multiple-choice questions of the learning level test. The content of the in-person sessions in the intervention group will be in accordance with the following categories:1. Content of the first session:At the beginning of the first session, the purpose of the research, how to implement flipped classroom training, individual and group tasks, and the general process of participating in the study are explained to the students. After obtaining written consent from the volunteers, the students are divided into groups of 6 to 8. Also, questionnaires related to the variables under study are completed by the participants. Finally, an introduction to the topic of the second session will be provided for mental preparation.2. Content of the second session:The educational content of the second session is dedicated to the basic concepts of wounds, the structures that make up the skin, types of wounds, wound assessment, the wound healing process, factors affecting the progress of wound healing, problems related to wound healing, and appropriate nursing measures in clients with impaired skin integrity. After reviewing the materials as a group and answering the questions, each group is faced with a relevant clinical scenario and is tasked with analyzing and formulating appropriate nursing measures. Subsequently, the representative of each group presents its findings to the group. The session ends with a general introduction to the topic of the next session.3. Content of the third session:In this session, the definition of pressure ulcer, the cause of pressure ulcer, types of pressure ulcer, pressure ulcer assessment, factors affecting the development of pressure ulcer, and areas at risk of pressure ulcer and factors affecting it are discussed. The training process is similar to the second session, and group activities focus on analyzing clinical scenarios based on the content presented. At the end, the researcher will provide an introduction to the next session.4. Content of the fourth session:The final session is dedicated to teaching concepts related to the prevention and treatment of pressure ulcers, familiarization with types of dressings and new technologies in wound management. In-person activities will also be carried out according to the pattern of previous sessions. At the end of this session, the research questionnaires will be completed by the students for the second time. Intervention 2: Control group: In the control group, like the intervention group, 4 flipped classroom training sessions will be provided with the same content as in the intervention group. In-person sessions will be held in exactly the same style and in accordance with the intervention group, with the only difference being that in the control group, the content of each session in the pre-class activity section will be uploaded by the researcher to the Navid system in the form of video content, and no training will be provided on artificial intelligence.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is There is no more information</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Fatemeh Shirazi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>School of Nursing and Midwifery (SA), Namazi Square</address>
        <city>shiraz</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>71393613119</zip>
        <telephone>+98 71 3647 4254</telephone>
        <email>shirazi_1393@yahoo.com</email>
        <affiliation>Shiraz University of Medical Sciences</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Fatemeh Shirazi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>School of Nursing and Midwifery (SA), Namazi Square</address>
        <city>shiraz</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>7193613119</zip>
        <telephone>+98 71 3647 4254</telephone>
        <email>shirazi_1393@yahoo.com</email>
        <affiliation>Shiraz University of Medical Sciences</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>First-semester nursing student who has taken the Fundamentals of Nursing Skills course
  Willingness to participate in the study
Age 18 to 30 years
Access to a smartphone or laptop
 Access to the internet</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>30 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>Failure to cooperate in continuing to participate in the study or being absent from more than one session of training
 Incomplete completion of questionnaires by 20% of the main questions
 Previous history of taking the course
 History of taking wound and dressing courses based on self-report</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Behavior</i_code>
      <i_code>Behavior</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: the intervention will begin with the introduction and training of artificial intelligence tools, in a non-face-to-face manner and three weeks before the wound training sessions. The training content at this stage includes the introduction of artificial intelligence chatbots and content production tools (introduction to different chatbots, how to access them, how to write prompts, how to produce content such as text and images, PowerPoint and video), which will be presented to students in the form of micro-learning in the form of shortened content with a duration of 3 to 5 minutes as offline educational content in the form of films and written texts on the WhatsApp platform. After selecting the participants, introducing the research and obtaining informed consent in person; the educational topic of wounds and nursing care will be carried out using the flipped classroom method and with content creation by students. The list of educational content of wounds and modern dressings and nursing care will be provided to students as a header to be used to coordinate the content in content creation. The books and articles of the day, which have been approved by the group professors, will be provided to students to use in content production. Students are required to produce content in the form of a video or PowerPoint with audio before the in-person session using artificial intelligence tools and according to the provided list of contents. It should be noted that each group must place individual tasks in content production along with the tools used at the beginning of the content. The content produced is evaluated by the researcher and the best content produced is selected in terms of completeness, novelty, conceptuality, and attractiveness. If necessary, it is edited, corrected, and completed, and the final version is uploaded to the Navid system. Students then answer five related multiple-choice questions individually before the in-person class. These questions will be different from the multiple-choice questions of the learning level test. The content of the in-person sessions in the intervention group will be in accordance with the following categories:1. Content of the first session:At the beginning of the first session, the purpose of the research, how to implement flipped classroom training, individual and group tasks, and the general process of participating in the study are explained to the students. After obtaining written consent from the volunteers, the students are divided into groups of 6 to 8. Also, questionnaires related to the variables under study are completed by the participants. Finally, an introduction to the topic of the second session will be provided for mental preparation.2. Content of the second session:The educational content of the second session is dedicated to the basic concepts of wounds, the structures that make up the skin, types of wounds, wound assessment, the wound healing process, factors affecting the progress of wound healing, problems related to wound healing, and appropriate nursing measures in clients with impaired skin integrity. After reviewing the materials as a group and answering the questions, each group is faced with a relevant clinical scenario and is tasked with analyzing and formulating appropriate nursing measures. Subsequently, the representative of each group presents its findings to the group. The session ends with a general introduction to the topic of the next session.3. Content of the third session:In this session, the definition of pressure ulcer, the cause of pressure ulcer, types of pressure ulcer, pressure ulcer assessment, factors affecting the development of pressure ulcer, and areas at risk of pressure ulcer and factors affecting it are discussed. The training process is similar to the second session, and group activities focus on analyzing clinical scenarios based on the content presented. At the end, the researcher will provide an introduction to the next session.4. Content of the fourth session:The final session is dedicated to teaching concepts related to the prevention and treatment of pressure ulcers, familiarization with types of dressings and new technologies in wound management. In-person activities will also be carried out according to the pattern of previous sessions. At the end of this session, the research questionnaires will be completed by the students for the second time.</i_keyword>
      <i_keyword>Control group: In the control group, like the intervention group, 4 flipped classroom training sessions will be provided with the same content as in the intervention group. In-person sessions will be held in exactly the same style and in accordance with the intervention group, with the only difference being that in the control group, the content of each session in the pre-class activity section will be uploaded by the researcher to the Navid system in the form of video content, and no training will be provided on artificial intelligence.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Learning Outcomes. Timepoint: In both groups, in the first in-person session, the pre-test forms will be completed by the students in person, and in the fourth teaching session, which is the end of the intervention, the post-test forms will be completed by the students for the second time in person. Method of measurement: A researcher-made test will be used to measure student learning. This test will contain 15 four-choice questions. A correct answer to each question will be worth 1 point and an incorrect answer will be worth 0 points, which will be a total of 15 questions, 15 points. Face and content validity will be reviewed by 3 faculty members who are familiar with teaching this content, and CVI will be calculated, and the Koder-Richardson statistical test will be used to confirm reliability.</prim_outcome>
      <prim_outcome>Academic Engagement. Timepoint: In both groups, in the first in-person session, the pre-test forms will be completed by the students in person, and in the fourth teaching session, which is the end of the intervention, the post-test forms will be completed by the students for the second time in person. Method of measurement: The Academic Engagement Questionnaire was designed and developed by Riv (2013) to measure academic engagement. This questionnaire has 17 questions and 4 dimensions, which are answered based on a seven-point Likert scale.</prim_outcome>
      <prim_outcome>Critical Thinking Disposition. Timepoint: In both groups, in the first in-person session, the pre-test forms will be completed by the students in person, and in the fourth teaching session, which is the end of the intervention, the post-test forms will be completed by the students for the second time in person. Method of measurement: To examine students' tendency to think critically, the Critical Thinking disposition Questionnaire, designed by Ricketts in the United States in 2003, will be used.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Shiraz University of Medical Sciences</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2025-10-18</approval_date>
        <contact_name>Research Ethics Committees of Schools of Nursing and Midwifery, Management and Medical Information</contact_name>
        <contact_address>Vice-Chancellor for Research, Shiraz University of Medical Sciences, Zand Blvd. Shiraz Fars Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
