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IRCT20251027067782N1 IRCT 2025-11-27 Islamic Azad University The effect of repetitive magnetic stimulation on movement and swallowing in patients with ischemic stroke Evaluation of the effect of repetitive extracerebral magnetic stimulation (rTMS) in improving motor performanceand swallowing disorders in patients with ischemic stroke 2025-12-07 anticipated 205 Recruiting https://irct.ir/trial/87226 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment, Other design features: This study is a semi-experimental (before–after) design in which ischemic stroke patients are evaluated before and after receiving repetitive transcranial magnetic stimulation (rTMS) in terms of motor and swallowing function. Due to the therapeutic nature of the intervention and ethical and practical limitations in establishing a control group, a before–after design was chosen so that each patient serves as their own control. N/A Ischemic Stroke. Intervention group: Patients with ischemic stroke receive repetitive transcranial magnetic stimulation according to the standard protocol. The intervention consists of stimulation of the primary motor cortex of the affected hemisphere at a frequency of ten hertz, an intensity equal to one hundred percent of the motor threshold, a total of one thousand five hundred pulses per session, and an approximate duration of twenty minutes. Treatment sessions are delivered five times per week for two consecutive weeks. No additional intervention is applied during the treatment period.. No - There is not a plan to make this available Justification or reason for not sharing IPD is Due to the sensitive nature of individual patient data in ischemic stroke populations and the substantial risk of re-identification even after de-identification procedures, the ethics committee has imposed specific restrictions on data sharing. To ensure maximum confidentiality and full compliance with ethical and legal requirements, the individual participant data from this study cannot be publicly shared at this time. No additional information is available.
public Amirali Akbari baghbaderani
No. 51, Baradaran Ziaei Alley, Before Payambar-e Gharbi, Shahid Mostafa Pazhuhandeh Blvd., Ayatollah Kashani Blvd., Janat Abad-e Jonubi, Tehran, Iran
Tehran Iran (Islamic Republic of) 1471945815 +98 21 4404 0483 Amiraliakbri1999@gmail.com Islamic Azad University scientific Amirali Akbari baghbaderani
No. 51, Baradaran Ziaei Alley, Before Payambar-e Gharbi, Shahid Mostafa Pazhuhandeh Blvd., Ayatollah Kashani Blvd., Janat Abad-e Jonubi, Tehran, Iran
Tehran Iran (Islamic Republic of) 1471945815 +98 21 4404 0483 Amiraliakbri1999@gmail.com Islamic Azad University Iran (Islamic Republic of) Confirmed ischemic stroke by CT or MRI Presence of motor or swallowing dysfunction after stroke At least two weeks post-stroke (clinically stable phase) Ability to attend therapy sessions Written informed consent obtained 25 years 65 years Both Hemorrhagic stroke History of epilepsy or active seizures Metallic implants or contraindicated medical devices for rTMS Severe psychiatric or cognitive disorders Inability to cooperate in therapy sessions I63 Cerebral infarction Treatment - Devices Intervention group: Patients with ischemic stroke receive repetitive transcranial magnetic stimulation according to the standard protocol. The intervention consists of stimulation of the primary motor cortex of the affected hemisphere at a frequency of ten hertz, an intensity equal to one hundred percent of the motor threshold, a total of one thousand five hundred pulses per session, and an approximate duration of twenty minutes. Treatment sessions are delivered five times per week for two consecutive weeks. No additional intervention is applied during the treatment period. Change in motor function score measured by the Fugl Meyer Assessment from before the intervention to after completion of the intervention. Timepoint: Measurement of motor function at baseline before the start of the intervention and after completion of the full course of repetitive transcranial magnetic stimulation sessions. Method of measurement: Motor function measurement using the Fugl Meyer Assessment administered by a trained rehabilitation specialist. Change in swallowing function score measured by the Functional Oral Intake Scale from before the intervention to after completion of the intervention. Timepoint: Measurement of swallowing function at baseline before the start of the intervention and after completion of the full course of repetitive transcranial magnetic stimulation sessions. Method of measurement: Swallowing function measurement using the Functional Oral Intake Scale administered by a trained speech therapist. Islamic Azad University Approved 2024-12-24 Biomedical Ethics Committee of Islamic Azad University, Tehran Medical Sciences Branch Tehran, Shahid Ghandi St., North of Sadr Bridge, Shariati St., Islamic Azad University, Tehran Medical Sciences Branch Tehran Tehran Iran (Islamic Republic of)