<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20251029067810N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2026-08-16</date_registration>
      <primary_sponsor>The University of tehran</primary_sponsor>
      <public_title>The effects of combining foam roller exercises and aerobic exercises on cytokine and adipokine levels in sedentary overweight elderly men.</public_title>
      <acronym></acronym>
      <scientific_title>Comparison of combined foam roller and aerobic exercises versus foam roller exercises alone on cytokine and adipokine levels in sedentary elderly overweight men</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2023-05-30</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>50</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/87252</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Other, Randomization description: Randomization Using Random Number Table Method.
In this method, a table was prepared containing numbers 1 to 31 arranged completely randomly. Each of the 31 subjects was assigned a number. For the starting point and the first desired number, a number was selected randomly by chance. From the starting point, numbers were read row by row, and for each of the 3 groups, numbers were extracted and assigned to the intervention and control groups.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Condition 1: Overweight in the elderly. Condition 2: physical inactivity in the elderly.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group 1: Foam Roller Group. The foam roller is a fitness tool used for myofascial release. In this study, 11 participants in the foam roller group performed foam roller exercises for 3 months, three days a week, at a specific time in a gym. The exercises in the foam roller group included upper and lower body workouts, which were conducted with a predetermined structure. The foam roller used in this intervention was manufactured in Taiwan. Intervention 2: Intervention group 2: foam roller - aerobic.This group consisted of 11 subjects, and the subjects exercised in a gym three days a week at a specific time for 3 months. The aerobic protocol consisted of 40 minutes of brisk walking or jogging at 50 to 60 percent of maximum heart rate reserve. Foam roller exercises included only lower body exercises. Intervention 3: Control group: without any intervention. From the control group, only blood samples, anthropometric measurements, and initial assessments were taken. Measurements and tests were performed once before the start of the training protocol and once 3 months later, after the completion of the intended exercises and interventions.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
Only part of the data can be shared
Data related to the main factors of the article, which include Interleukin-6, Irisin, Adiponectin, and glycophorin.

When:
Six months after the results were published

To whom:
Lecturers and researchers employed by universities

Conditions:
Keeping the authors of the article informed

Where to obtain:
Hamidreza shakermahani
Hamidreza.shaker@ut.ac.ir
09211986959

How to obtain:
It will be sent after talking with the author within the appropriate timeframe

Comments:
</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Hamidreza shakermahani</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Second house on the left, Lane 19, Hemmati-Far Street.</address>
        <city>Kerman</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>7618441317</zip>
        <telephone>+98 34 3261 0540</telephone>
        <email>hamidreza.shaker@ut.ac.ir</email>
        <affiliation>The University of tehran</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Hamidreza shakermahani</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Second house on the left, 19 Alley, Hemmatifar Street.</address>
        <city>Kerman</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>7618441317</zip>
        <telephone>+98 34 3261 0540</telephone>
        <email>hamidreza.shaker@ut.ac.ir</email>
        <affiliation>The University of tehran</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>They do not engage in regular physical activity throughout the week (at least three days per week for 30 minutes).
Participants should not have a history of smoking or drinking alcoholic beverages.
Participants should not have undergone any surgery in the three months prior to the start of the exercise protocol and should not have had any fractures in their limbs.
Overweight older adults aged 60 to 70 years were enrolled in the study protocol.</inclusion_criteria>
      <agemin>60 years</agemin>
      <agemax>70 years</agemax>
      <gender>Male</gender>
      <exclusion_criteria>Presence of specific diseases such as ...(MS, cancer, Parkinson's)
History of smoking and alcohol consumption
Undergoing specific surgery within 3 months prior to the start of the exercise protocol
Presence of fractures in the limbs</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>E66.3</hc_code>
      <hc_code>Z72.3</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Overweight</hc_keyword>
      <hc_keyword>Lack of physical exercise</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Other</i_code>
      <i_code>Other</i_code>
      <i_code>Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group 1: Foam Roller Group. The foam roller is a fitness tool used for myofascial release. In this study, 11 participants in the foam roller group performed foam roller exercises for 3 months, three days a week, at a specific time in a gym. The exercises in the foam roller group included upper and lower body workouts, which were conducted with a predetermined structure. The foam roller used in this intervention was manufactured in Taiwan.</i_keyword>
      <i_keyword>Intervention group 2: foam roller - aerobic.This group consisted of 11 subjects, and the subjects exercised in a gym three days a week at a specific time for 3 months. The aerobic protocol consisted of 40 minutes of brisk walking or jogging at 50 to 60 percent of maximum heart rate reserve. Foam roller exercises included only lower body exercises.</i_keyword>
      <i_keyword>Control group: without any intervention. From the control group, only blood samples, anthropometric measurements, and initial assessments were taken. Measurements and tests were performed once before the start of the training protocol and once 3 months later, after the completion of the intended exercises and interventions.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Serum irisin level. Timepoint: Before the start of the intervention and after 3 months at the end of the exercises. Method of measurement: Through the ELISA test.</prim_outcome>
      <prim_outcome>Serum interleukin-6 level. Timepoint: Before the start of the intervention and after 3 months at the end of the exercises. Method of measurement: Through the ELISA test.</prim_outcome>
      <prim_outcome>Serum adipolin level. Timepoint: Before the start of the intervention and after 3 months at the end of the exercises. Method of measurement: Through the ELISA test.</prim_outcome>
      <prim_outcome>Serum glycophorin level. Timepoint: Before the start of the intervention and after 3 months at the end of the exercises. Method of measurement: Through the ELISA test.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>The University of tehran</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2023-07-02</approval_date>
        <contact_name>Ethics and Research Committee of the Faculty of Sports Sciences and Health, University of Tehran</contact_name>
        <contact_address>Opposite the Daneshgah Alley, between 15th and 16th streets, above Jalal Al-Ahmad intersection, North Kargar Street Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
