IRCT20251229068487N1 IRCT 2026-02-16 Zahedan University of Medical Sciences Evaluation of Leukocyte & Platelet-Rich Fibrin Effect on Wound Healing Evaluation of Leukocyte & Platelet-Rich Fibrin Effect on Wound Healing Following Third Mandibular Molar Extraction in Zahedan Dental University Patients 2026-02-19 anticipated 30 Complete https://irct.ir/trial/88417 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: wax-sealed envelope are used.Envelops containing name Left or Right are prepared randomly.After the third molar removed by surgeon, the pockets are opened by surgical assistant, and according to this, the assistant inserts the L-PRF into desired cavity. One side is selected as the Intervention group, and the other side is only sutured as Control group, Blinding description: During surgery,after the surgeon extract the wisdom teeth from both sides, they leave the operating room and the surgical assistant,based on randomly opened envelope, place the L-PRF inside one of the sockets and sutures each socket with same suture. These processes are carried out by a surgeon and surgical assistant, neither of whom participates in data analysis or evaluation stages. N/A Condition 1: Dry socket after third molar removal. Condition 2: Inflammation & Bleeding after third molar removal. Intervention 1: Intervention group: In each patient,After extraction of both sides,one extraction socket is randomly treated with L-PRF and sutured.Patients will follow up in terms of wound healing for 2 weeks. Intervention 2: Control group: In each patient,After extraction of both sides,one extraction socket without any intervention sutured.Patients will follow up in terms of wound healing for 2 weeks. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is -