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IRCT20241205063953N4 IRCT 2026-01-19 Islamic Azad University Elastic Band Resistance Training and liver disease in Postmenopausal Women Effect of Elastic Band Resistance Training on irisin, liver enzymes, Hepatic Steatosis and Metabolic Outcomes in Postmenopausal Women with MASLD 2026-01-25 anticipated 54 Complete https://irct.ir/trial/88605 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, simple randomization was used to assign participants to study groups. The randomization unit was individual, meaning that each person was independently assigned to one of the two groups: elastic band resistance training group (n = 27) or the control group (n = 27). The randomization tool was EXECL software which generated the random sequence before the study began to prevent allocation bias. Allocation concealment was ensured using sealed and numbered opaque envelopes containing the group assignment for each participant. These envelopes were opened only after a participant's eligibility was confirmed by an independent researcher not involved in the randomization process. Stratified randomization was applied based on age to ensure balance across groups for these key variables. N/A Liver diseases. Intervention 1: Intervention group: Elastic band resistance training group. This group practiced elastic band resistance training under the supervision of instructors for 8weeks, 3 sessions per week, 60 minutes per session. Intervention 2: Control group: No sports activities were involved during the research. Yes - There is a plan to make this available What will be shared: All data without participant names When: 6 months after publication of the article To whom: University students and professors Conditions: For future research Where to obtain: To the researchers of this study How to obtain: By email to researchers Comments:
public َAkram Jafari
Rahmatieh, Islamic Azad University Shahrekord Branch
Shahrekord Iran (Islamic Republic of) 8818630003 +98 912 547 9267 Jafari.akm@gmail.com Islamic Azad University scientific Akram Jafari
Rahmatieh, Islamic Azad University Shahrekord Branch
Shahrekord Iran (Islamic Republic of) 8817630003 +98 912 547 9267 Jafari.akm@gmail.com Islamic Azad University Iran (Islamic Republic of) Body mass index between 40 and 50 kg/m² Stable body weight (±3%) during the preceding three months No engagement in structured exercise training within the previous six months. 55 years 75 years Female K75.81 Nonalcoholic steatohepatitis (NASH) Treatment - Other Other Intervention group: Elastic band resistance training group. This group practiced elastic band resistance training under the supervision of instructors for 8weeks, 3 sessions per week, 60 minutes per session. Control group: No sports activities were involved during the research. Hepatic Steatosis. Timepoint: 48 hours before and after 8 weeks of research. Method of measurement: Method for quantifying liver fat content (CAP). ALT. Timepoint: 48 hours before and after 8 weeks of research. Method of measurement: ALT levels were measured using a commercial kit (Pars Azmoon, Tehran, Iran) with enzymatic methods. AST. Timepoint: 48 hours before and after 8 weeks of research. Method of measurement: AST levels were measured using a commercial kit (Pars Azmoon, Tehran, Iran) with enzymatic methods. Irisin. Timepoint: 48 hours before and after 8 weeks of research. Method of measurement: Measured using the enzyme-linked immunosorbent assay (ELISA) method with an enzyme immunoassay kit (Phoenix Pharmaceuticals®, Burlingame, USA). Insulin. Timepoint: 48 hours before and after 8 weeks of research. Method of measurement: Insulin levels were measured using the enzyme-linked immunosorbent assay (ELISA) method and equipment (ZellBio, Ulm, Germany). Glucose. Timepoint: 48 hours before and after 8 weeks of research. Method of measurement: Glucose levels were measured using a commercial kit (Pars Azmoon, Tehran, Iran) with photometric and enzymatic methods. Islamic Azad University Approved 2020-02-08 Islamic Azad University Shahrekord Branch Rahmatieh, Islamic Azad University Shahrekord Branch Shahrekord Chahar-Mahal-va-Bakhtiari Iran (Islamic Republic of)