]>
IRCT20260122068639N1 IRCT 2026-02-16 Kerman University of Medical Sciences anesthesia in root canal retreatment A comparison between anesthetic efficacy of articaine and lidocaine secondary endodontic treatment in mandibular molar teeth : A randomized clinical trial 2026-02-14 anticipated 60 Complete https://irct.ir/trial/88751 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Crossover, Purpose: Treatment, Randomization description: Patients will be randomly divided into two groups, Group A and Group B: Lidocaine VS Articaine (Men) and Lidocaine VS Articaine (Women), using the website www.SealedEnvelope.com. Each patient, after entering the study, will determine their group by selecting the word "Randomization", Blinding description: The anesthetic injection is performed by two endodontic specialty residents (other than the main operator) who have rehearsed and calibrated the block and infiltration injection techniques in a separate session. N/A Root canal retreatment of mandibular molars. Intervention 1: Intervention group: Use of supplementary infiltration injection of Articaine after mandibular block injection with Lidocaine in root canal retreatment of manibular molars. Intervention 2: Control group: Use of mandibular block injection with Lidocaine in root canal retreatment of manibular molars. Yes - There is a plan to make this available What will be shared: A portion of the data, such as information related to the main message or similar items, can be shared When: The access period begins one year after the results are published To whom: It will only be available to researchers employed at academic and scientific institutions Conditions: Use of the information is permitted solely for scientific purposes Where to obtain: Email address: m.moradinia.g@gmail.com How to obtain: By sending an email to the mentioned address, the documentation will reach them after one week Comments:
public Hamed Manouchehrifar
Shafa street . Kerman university of medical sciences
Kerman Iran (Islamic Republic of) 7618759689 +98 914 315 4323 hamed_man61@yahoo.com Kerman University of Medical Sciences scientific Hamed Manouchehrifar
Shafa street . Kerman university of medical sciences
Kerman Iran (Islamic Republic of) 7618759689 +98 914 315 4323 hamed_man61@yahoo.com Kerman University of Medical Sciences Iran (Islamic Republic of) – First or second mandibular molars with a history of root canal treatment having a Periapical Index (PAI) score of 1, 2, or 3. Teeth previously treated with root canal therapy but unsuccessful and having developed apical periodontitis (AP). Individuals with a spontaneous pain score of less than 54 mm on the HP-VAS scale Teeth with radiographically poor-quality root canal fillings. Teeth with failed or insufficient coronal restoration requiring root canal retreatment. Patients aged 18 to 65 years Patients with ASA I and ASA II Patients without acute pain or extracoral swelling Patients with acute apical abscess Patients who voluntarily participate in the study and are available for follow-up Absence of severe periodontal problem in the tooth in question Teeth with prefabricated posts 18 years 65 years Both Individuals with a spontaneous pain score greater than 54 on the HP-VAS scale Patients whose retreatment requires two sessions.– Teeth with internal or external root resorption Teeth with vertical root fracture or dental crack Teeth with open or immature apex Patients with systemic diseases (such as bone metabolism disorders) Patients taking medications affecting bone metabolism Patients with acute pain who have taken analgesics in the past 24 hours Patients who did not attend follow-up sessions third molars Presence of severe periodontal disease rendering the tooth unsuitable for endodontic treatment Periodontal probing depth greater than 3 mm. Root canal treatment extending beyond the canal length and over instrumentation Teeth with cast posts or broken files inside the canal Patients with contraindications to NSAIDs Patients who experience treatment errors during retreatment Patients who are accidentally over-instrumented during the procedure Patients in whom post-operative radiography shows any extrusion of the root canal filling material Teeth with extensive caries making restoration impossible K04.9 Other and unspecified diseases of pulp and periapical tissues Treatment - Other Treatment - Other Intervention group: Use of supplementary infiltration injection of Articaine after mandibular block injection with Lidocaine in root canal retreatment of manibular molars Control group: Use of mandibular block injection with Lidocaine in root canal retreatment of manibular molars Pain score in the Heft-Parker Visual Analog Scale (HP-VAS) questionnaire. Timepoint: Before the start of treatmentDuring the injectionDuring removal of the coronal restorationDuring removal of gutta-percha from the canalsDuring canal preparation and irrigationDuring obturationImmediately after completion of the procedure,6 hours after the procedure,12 hours after the procedure, 24 hours after the procedure, 2 days after the procedure, 3 days after the procedure،7 days after the procedure. Method of measurement: Heft-Parker Visual Analog Scale (HP-VAS) questionnaire. Quality of life score. Timepoint: Before the start of treatment, 7 days after treatment. Method of measurement: Oral Health Impact Profile-14 (OHIP-14) questionnaire. Kerman University of Medical Sciences Approved 2025-11-02 Kerman University of Medical Sciences Ethics Committee Kerman, Jomhori Esalmi Blvd, Shafa Street Kerman Kerman Iran (Islamic Republic of)