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IRCT20250113064368N3 IRCT 2026-04-13 Islamic Azad University Investigating the Effect of Oral Curcumin on Perineal Pain Severity and Episiotomy Wound Healing Speed in Postpartum Women Undergoing Normal Delivery Investigating the Effect of Oral Curcumin on Perineal Pain Severity and Episiotomy Wound Healing Speed in Postpartum Women Undergoing Normal Delivery: A Clinical Trial Study in Selected Centers of Isfahan Province 2026-04-04 anticipated 59 Complete https://irct.ir/trial/89378 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Treatment, Other design features: Pre-intervention: Baseline information including age, height, weight, medical history, and delivery status will be recorded.Baseline Assessment: Pain (VAS) and wound status (REEDA) will be measured and recorded 4 hours post-episiotomy and prior to the intervention.Follow-up and Re-assessment: Pain intensity (VAS) and wound status (REEDA) will be assessed by a trained researcher on the seventh and tenth days postpartum.Standardization: All units will have the same type of episiotomy, repair method, suture type, amount of local anesthetic prior to incision, and type of adjunctive analgesics to minimize confounding variables, Randomization description: Randomization was conducted through allocation based on the sequential inpatient file numbers. After eligibility confirmation and prior to any intervention, each participant received a unique hospital admission file number. According to a prespecified odd–even allocation rule, participants with even numbers were assigned to the control group, while those with odd numbers were allocated to the intervention group. N/A Episiotomy Wound. Intervention 1: Intervention group: Receiving curcumin supplements up to day 10 postpartum. Intervention 2: Control group: Without curcumin consumption. No - There is not a plan to make this available Justification or reason for not sharing IPD is Due to the preservation of confidentiality, there are no plans for its publication.
public Mina Jouzi
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Najafabad Iran (Islamic Republic of) ۸۵۱۴۱۴۳۱۳۱ +98 31 4229 2581 minajouzi@gmail.com Islamic Azad University scientific Mina Jouzi
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Najafabad Iran (Islamic Republic of) ۸۵۱۴۱۴۳۱۳۱ +98 31 4229 2581 minajouzi@gmail.com Islamic Azad University Iran (Islamic Republic of) Gestational age between 37 to 42 full weeks presence of a single live fetus normal body mass index mediolateral episiotomy women must be breastfeeding and willing to continue breastfeeding no limit no limit Female no sensitivity to curcumin no consumption of specific analgesics no use of specific medications (glucocorticoids, anticoagulants, chemotherapy, immunosuppressants, radiotherapy) no history of chronic systemic diseases (cardiac, renal, pulmonary, coagulation disorders, immunodeficiency, connective tissue disorders, diabetes, anemia, psychiatric illnesses, hemophilia, and malnutrition) Treatment - Drugs Treatment - Drugs Intervention group: Receiving curcumin supplements up to day 10 postpartum. Control group: Without curcumin consumption. Severity of Perineal Pain and Healing Speed of Episiotomy Wound. Timepoint: Pain (VAS) and Wound Status (REEDA) are measured and recorded 4 hours after episiotomy (before the intervention, on the seventh and tenth day after daily curcumin consumption). Method of measurement: The Visual Analogue Scale (VAS) tool for assessing pain intensity and the REEDA (Redness, Edema, Echymosis, Discharge, Approximation) tool for assessing wound status. Islamic Azad University Approved 2026-04-04 The Ethics Committee of Najafabad Branch, Islamic Azad University University Boulevard Najafabad Isfehan Iran (Islamic Republic of)