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IRCT20260309068977N2 IRCT 2026-05-12 Shahid Beheshti University of Medical Sciences Comparison of monocryl and nylon suture in CTR surgery Comparison of the effect of surgical site closure with Monocrly Vs. Nylon sutures on the incidence, severity, and duration of pillar pain and surgical site scar in patients with carpal tunnel syndrome 2026-03-01 anticipated 70 Recruiting https://irct.ir/trial/89443 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization will be performed in this study. The random sequence will be generated using the RAND function in Microsoft Excel software by an individual not involved in the surgical team. to ensure allocation concealment, sequentially numbered, opaque, sealed envelopes will be used; the intervention type for each patient will be revealed only in the operating room after the envelope is opened by a surgical assistant, Blinding description: At the end of the operation, exactly before closing the surgical site, the surgeon is informed of the type of suture to be used for the patient. In this way, the surgical technique will be identical in all patients. All postoperative visits, data recording, and data analysis are performed by someone who is unaware of the study's objectives and the groupings. N/A Carpal tunnel syndrome. Intervention 1: Intervention group: Open (standard) carpal tunnel release surgical site closure using 4-0 Monocryl suture (manufactured by Ethicon, USA) in a subcuticular manner. Intervention 2: Control group: Open (standard) carpal tunnel release surgical site closure using 4-0 Nylon suture (manufactured by Supa, Iran) in a subcuticular manner. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Due to patient confidentiality
public Mohamad Hossein Baqeri pour
15th khordad Hospital, Shahid Azodi Street
Tehran Iran (Islamic Republic of) 1598763513 +98 21 8894 3434 graypackage@gmail.com Shahid Beheshti University of Medical Sciences scientific Mohamad Hossein Baqeri pour
15th khordad Hospital, Shahid Azodi Street
Tehran Iran (Islamic Republic of) 1598763513 +98 21 8894 3434 graypackage@gmail.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) Patients with a confirmed diagnosis of carpal tunnel syndrome patients who are candidates for standard carpal tunnel release surgery Patients who have provided written informed consent to participate in the study 18 years no limit Both Age under 18 years or individuals unable to make decision and provide informed consent Individuals with diabetes mellitus Individuals with systemic diseases affecting wound healing, such as collagen vascular diseases Individuals with a history of fracture or extensive soft tissue injury in the hand affected by carpal tunnel syndrome Individuals consuming chemotherapy drugs or corticosteroids individuals with recurrent carpal tunnel syndrome G56.0 Carpal tunnel syndrome Treatment - Surgery Treatment - Surgery Intervention group: Open (standard) carpal tunnel release surgical site closure using 4-0 Monocryl suture (manufactured by Ethicon, USA) in a subcuticular manner. Control group: Open (standard) carpal tunnel release surgical site closure using 4-0 Nylon suture (manufactured by Supa, Iran) in a subcuticular manner. Prevalence, severity and duration of Pillar pain. Timepoint: 1,6,12,24 weeks post operation. Method of measurement: Visual analogue scale (VAS). Surgical site Scar quality. Timepoint: 1, 6, 12 and 24 weeks post operation. Method of measurement: Vancouver scar scale (VSS). Shahid Beheshti University of Medical Sciences Approved 2026-02-24 Ethics committee of Shahid Beheshti University of Medical Sciences 15th Khordad hospital, Shaid Azodi Street Tehran Tehran Iran (Islamic Republic of)