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IRCT201112248509N1 IRCT 2012-01-06 Urology and Nephrology Research Center of Shahid Beheshti University of Medical Sciences The effect of treatment with recombinant human follicle stimulating hormone (rhFSH), human chorionic gonadotropin (HCG) and human menopausal gonadotropin (HMG) on semen parameters after varicocelectomy: a randomized clinical trial. Comparison of the effects of treatment with recombinant human follicle stimulating hormone (rhFSH), human chorionic gonadotropin (HCG) and human menopausal gonadotropin (HMG) on semen parameters after varicocelectomy in patients with varicocele 2010-01-01 anticipated 120 Complete https://irct.ir/trial/9009 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A infertility. Intervention 1: Patients will be treated with 5000 IU human chorionic gonadotropin weekly intramuscular for 3 months. Intervention 2: Patients will be treated with 75 IU human menopausal gonadotropin three times a week sub coutaneous for 3 months. Intervention 3: Patients will be treated with 75 IU recombinant human follicle-stimulating hormone three times a week sub coutaneous for 3 months. Intervention 4: no medical treatment after varicocelectomy.
public Mohammad Ali Amirzargar
Urology Department, Hamadan University of Medical Sciences, University square, Hamadan
hamadan Iran (Islamic Republic of) +98 81 1823 2858 dr_amirzargar@yahoo.com Department of Urology, Hamadan University of Medical Sciences scientific Mohammad Ali Amirzargar
Urology Department, Hamadan University of Medical Sciences, University square, Hamadan
hamadan Iran (Islamic Republic of) +98 81 1823 2858 dr_amirzargar@yahoo.com Department of Urology, Hamadan University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Inclusion criteria: infertility after 12 months of unprotected intercourse; male factor infertility due to varicocele; spontaneous onset of maturation and normal sexual development Exclusion criteria: presence of infertility due to any other factor especially female infertility; systemic disease; underlying testis abnormalities; abnormal reproductive hormone levels. no limit no limit Male N46 Male infertility Treatment - Drugs Treatment - Drugs Treatment - Drugs Treatment - Drugs Patients will be treated with 5000 IU human chorionic gonadotropin weekly intramuscular for 3 months. Patients will be treated with 75 IU human menopausal gonadotropin three times a week sub coutaneous for 3 months. Patients will be treated with 75 IU recombinant human follicle-stimulating hormone three times a week sub coutaneous for 3 months. no medical treatment after varicocelectomy Sperm parameters. Timepoint: before initiation of treatment and further control examinations were performed 8 to 10 weeks after the completion of each period of treatment. Method of measurement: spermogram. Pregnancy. Timepoint: 6 month. Method of measurement: bHCG. Hamadan University of Medical Sciences Urology and Nephrology Research Center of Shahid Beheshti University of Medical Sciences Hamadan University of Medical Sciences Approved 2007-06-23 Urology and Nephrology Research Center (UNRC), Shahid Labbafinejad Medical Center labafinejhad hospital tehran Iran (Islamic Republic of)