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IRCT20260605069646N1 IRCT 2026-07-10 Razi Univeristy Effect of Six‑Week Corrective Exercise and Collagen‑Vitamin C Supplementation on Pain, Function, and Quality of Life in Female Athletes with Achilles Tendinopathy The Effect of Six Weeks of Corrective Exercises Combined with Hydrolyzed Collagen and Vitamin C Supplementation on Pain, Function, and Quality of Life in Female Athletes Players with Achilles Tendinopathy 2026-08-01 anticipated 30 Pending https://irct.ir/trial/90676 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Randomization is performed using block randomization with block sizes of 4 (or 6). The allocation sequence is generated by statistical software or a random number table and placed in sequentially numbered, opaque, sealed envelopes. Group allocation is carried out by an independent individual (not involved in assessment or intervention delivery) to ensure allocation concealment. The outcome assessor and participants remain blinded to group assignment (assessor‑blinded design), Blinding description: Blinding is applied only to participants. Both groups receive the same corrective exercise program, but participants are unaware of which supplement they are taking. The active supplement (collagen + vitamin C) and placebo are completely identical in appearance, odor, taste, color, size, and packaging, and are coded by an individual independent of the research team. Thus, participants do not know whether they are in the supplement or placebo group. N/A Female Athletes. Intervention 1: Intervention group: The intervention group (n=15) consumes 30 g of hydrolyzed collagen plus 500 mg of vitamin C one hour before each corrective exercise session, performed three times per week for six weeks. Intervention 2: Control group: The control group (n=15) consumes a placebo (maltodextrin plus 500 mg of vitamin C) one hour before each corrective exercise session, performed three times per week for six weeks, following the same exercise protocol as the intervention group. Yes - There is a plan to make this available What will be shared: All data will be recorded in the SPSS software and will be available When: Availability will start nine months after publishing all papers To whom: Only available for researchers in academic and scientific institutions Conditions: All data can be used as a reference Where to obtain: asalbesanj@gmail.com How to obtain: All data can be used as a reference Comments:
public Hidar Menochari
No. 9, Razi University, Daneshgah Boulevard, Taq Bostan Street, Kermanshah City
Kermanshah Iran (Islamic Republic of) 6714967346 +98 83 3428 3270 mhaidary2000@yahoo.com Razi University scientific Menocher Hidary
No. 9, Razi University, Daneshgah Boulevard, Taq Bostan Street, Kermanshah City
Kermanshah Iran (Islamic Republic of) 6714967346 +98 83 3428 3270 mhaidary2000@yahoo.com Razi University Iran (Islamic Republic of) Clinical diagnosis of mid‑portion Achilles tendinopathy (pain and tenderness ۲–۶ cm above insertion) confirmed by a specialist or imaging (ultrasound/MRI). Recreational to semi‑professional female athletes with at least ۳ exercise sessions per week, aged ۱۸–۴۵ years. Pain intensity ≥ ۳/۱۰ on Visual Analogue Scale (VAS) during daily or sports activity for at least the past ۴ weeks. 18 years 28 years Female History of Achilles surgery, complete rupture, corticosteroid or PRP injection in the last ۶ months Systemic diseases affecting tissue repair (uncontrolled diabetes, rheumatoid arthritis, renal failure) or allergy to collagen/vitamin C. Pregnancy, lactation, regular use of analgesics/NSAIDs in the ۲ weeks prior to the study, or concurrent participation in other targeted physiotherapy/exercise interventions for Achilles. Prevention Prevention Intervention group: The intervention group (n=15) consumes 30 g of hydrolyzed collagen plus 500 mg of vitamin C one hour before each corrective exercise session, performed three times per week for six weeks. Control group: The control group (n=15) consumes a placebo (maltodextrin plus 500 mg of vitamin C) one hour before each corrective exercise session, performed three times per week for six weeks, following the same exercise protocol as the intervention group. Pain. Timepoint: Measurement time points are two: baseline (week 0) and post‑test (week 6). Method of measurement: pain via Visual Analogue Scale (VAS, 0‑10) during sports activity. Achilles‑specific function. Timepoint: Measurement time points are two: baseline (week 0) and post‑test (week 6). Method of measurement: function via the VISA‑A questionnaire (8 items, 0‑100). Quality of life/daily functional. Timepoint: Measurement time points are two: baseline (week 0) and post‑test (week 6). Method of measurement: Quality of life/daily function via the Lower Extremity Functional Scale (LEFS, 20 items, 0‑80). Razi Univeristy Approved 2026-05-12 Ethics Committee of Razi University of Kermanshah No. 8, Razi University, Daneshgah Boulevard, Taq Bostan Street, Kermanshah, Iran Kermanshah Kermanshah Iran (Islamic Republic of)