IRCT201512028612N3 IRCT 2016-01-22 Tehran University of Medical Sciences Effect of an immuno-suppresive medication (cyclosporine) on brain tumor patients survival A Clinical trial to assess the effects of short-term administration of cyclosporine on survival of patients with glioblastoma multiforme tumor surgery 2014-07-23 anticipated 40 Complete https://irct.ir/trial/9118 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: A computer-generated sequence with a block size of 4 patients was used for randomization. The patients were assigned consecutive numbers based on their order of enrolment in the study. Thus, unblinded pharmacists who were otherwise uninvolved in study conduct obtained randomized treatment assignments and managed study treatment, Blinding description: Patients were allocated to group A and B and received envelopes labeled A and B that contained Cyclosporine or placebo after surgery. Hence, neither the patients nor all investigators were aware of the drug contents and group allocation. 2-3 glioblastoma multiform. Intervention 1: Infusion of 2.5 mg/kg cyclosporine over first 2 hours post operation and will be continued with the dose of 5mg/kg /day for 72 hours. Intervention 2: control group: routine care of post op GBM patients. Yes - There is a plan to make this available What will be shared: Publish as scintifice article When: from 2021 To whom: Researchers Conditions: To design future studies Where to obtain: Dr. Alireza Khoshnevisan How to obtain: Formal request to principal researcher of study Comments: