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IRCT20260706070085N1 IRCT 2026-07-20 Combined Military Hospital Comparison of sphenopalatine ganglion block via transmucosal and transcoronoid approach for trigeminal autonomic cephalgia Comparison of sphenopalatine ganglion block via transmucosal and transcoronoid approach for trigeminal autonomic cephalgia 2026-07-15 anticipated 46 Recruiting https://irct.ir/trial/91476 interventional Randomization: Not randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Blinding description: Patients were unaware of the type of intervention being done to avoid any bias. 3 Trigeminal autonomic cephalalgias (TACs), including cluster headache and related disorders characterized by unilateral trigeminal pain with ipsilateral autonomic features, represent a relatively uncommon yet highly disabling group of primary headache disorders.. Intervention 1: Intervention group: Group A underwent sphenopalatine ganglion (SPG) block via the transmucosal approach. Intervention 2: Intervention group: Group B received the block through fluoroscopy guided transcoronoid approach. Yes - There is a plan to make this available What will be shared: Comparison of sphenopalatine ganglion block via transmucosal and transcoronoid approach for trigeminal autonomic cephalgia When: 6 months after Publication To whom: Journal publishing article Conditions: Journal publishing it Where to obtain: Journal publishing it How to obtain: Can be requested from Journal publishing it Comments:
public Khurram Liaqat
Tamiz Ud Din Road
Rawalpindi Pakistan 000000 +92 300 9834841 drkhurramliaqut@gmail.com Combined Military Hospital Rawalpindi scientific Khurram Liaqat
Tamiz Ud Din Road
Rawalpindi Pakistan 000000 +92 300 9834841 drkhurramliaqut@gmail.com Combined Military Hospital Rawalpindi Pakistan Patients aged 18–65 years with a clinical diagnosis of trigeminal autonomic cephalalgia were included. Eligible participants were those with inadequate response to at least six months of standard oral pharmacotherapy (including amitriptyline, duloxetine, venlafaxine, pregabalin or gabapentin) and who reported moderate to severe pain intensity (defined as a Numeric Rating Scale - NRS score greater than 6). Only patients without evidence of secondary headache disorders or underlying dental or palatal pathology were enrolled. 18 years 65 years Both Individuals with identifiable dental or palatal abnormalities contributing to facial pain Patients with secondary headache etiologies such as intracranial tumors or hemorrhage, patients with structural abnormalities including cleft lip/ palate or nasal septal defects, history of trauma or surgical intervention Patients with significant coagulopathy, hepatic or renal dysfunction, as well as those with a history of malignancy, were excluded from the study. G44.0 Cluster headaches and other trigeminal autonomic cephalgias (TAC) Treatment - Other Treatment - Other Intervention group: Group A underwent sphenopalatine ganglion (SPG) block via the transmucosal approach Intervention group: Group B received the block through fluoroscopy guided transcoronoid approach. The primary outcome was the mean change in NRS score from baseline to one month. Timepoint: Follow-up assessments were conducted at one week and one month after the intervention. Method of measurement: Pain intensity was recorded using the Numeric Rating Scale at each follow-up visit. Combined Military Hospital Approved 2026-05-28 Combined Military Hospital Tamiz ud Din Road Rawalpindi Punjab Pakistan