<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20180521039762N8</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2026-07-22</date_registration>
      <primary_sponsor>Payame Noor University</primary_sponsor>
      <public_title>Effect of Neuromuscular Exercises on Balance and Performance in Adolescent Female Soccer Players with Dynamic Knee Valgus</public_title>
      <acronym></acronym>
      <scientific_title>The Effect of Neuromuscular Exercises on Balance, Performance, and Jump-Landing Patterns in Adolescent Female Soccer Players with Dynamic Knee Valgus</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2026-08-23</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>40</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/91793</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: After the initial screening and confirmation of the eligibility criteria, 40 eligible female soccer players will be enrolled in the study. Randomization will be performed using a simple individual-level method. The random allocation sequence will be generated using the random number generation function in Microsoft Excel. A random number will be assigned to each participant, and the participants will then be sorted in ascending order based on these numbers. They will subsequently be allocated in a 1:1 ratio to the neuromuscular exercise group and the control group. Group allocation will be performed after completion of the baseline assessments. The random sequence will be kept concealed until the final allocation, Blinding description: Because of the nature of the exercise intervention, blinding of the participants will not be possible. However, the assessors of the functional and biomechanical tests and the statistical data analyst will be blinded to group allocation. This approach will be used to reduce measurement and analysis bias.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Dynamic knee valgus.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: Implementation of a neuromuscular training protocol focusing on improving motor control, balance, and landing pattern modification. The training will be performed for 8 weeks, 3 sessions per week, with each session lasting 40 to 50 minutes under direct supervision. The training program consists of the following components: warm-up (5 to 10 minutes of light running and dynamic stretching), proprioception and balance exercises (15 minutes on stable and unstable surfaces), plyometric and landing modification exercises (15 minutes of various jumps with emphasis on proper knee alignment and soft landing), core and hip stabilizer strengthening exercises (10 minutes), and cool-down (5 minutes of static stretching). Intervention 2: Control group: Subjects in this group will not receive any additional training or exercise intervention outside of their daily routine and regular soccer team training during the 8-week study period, and will only continue their routine sports activities.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>No - There is not a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for not sharing IPD is Due to the confidentiality of the adolescent participants’ personal data and to comply with research ethics principles, individual participant data will not be shared.</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Afshin Moghadasi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Payame Noor University, Nakhl St, Artesh Blvd, Tehran, Tehran Province, Iran</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>193954697</zip>
        <telephone>+98 21 2332 0000</telephone>
        <email>moghadasi@pnu.ac.ir</email>
        <affiliation>Payame Noor University</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Afshin Moghadasi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Payame Noor University, Nakhl St, Artesh Blvd, Tehran, Tehran Province, Iran</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>193954697</zip>
        <telephone>+98 21 2332 0000</telephone>
        <email>moghadasi@pnu.ac.ir</email>
        <affiliation>Payame Noor University</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Female sex
Age 14 to 17 years
Active membership in a soccer team and regular participation in training sessions
At least 3 years of regular soccer training experience
Presence of dynamic knee valgus based on the Landing Error Scoring System screening test</inclusion_criteria>
      <agemin>14 years</agemin>
      <agemax>17 years</agemax>
      <gender>Female</gender>
      <exclusion_criteria>History of acute or chronic injury in the lower extremities, pelvis, or spine during the past 6 months
History of surgery affecting the lower extremities, especially anterior cruciate ligament surgery
Presence of known neurological, musculoskeletal, or balance disorders
Use of medications that affect balance or motor performance</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M21.0</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Valgus deformity</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>N/A</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: Implementation of a neuromuscular training protocol focusing on improving motor control, balance, and landing pattern modification. The training will be performed for 8 weeks, 3 sessions per week, with each session lasting 40 to 50 minutes under direct supervision. The training program consists of the following components: warm-up (5 to 10 minutes of light running and dynamic stretching), proprioception and balance exercises (15 minutes on stable and unstable surfaces), plyometric and landing modification exercises (15 minutes of various jumps with emphasis on proper knee alignment and soft landing), core and hip stabilizer strengthening exercises (10 minutes), and cool-down (5 minutes of static stretching).</i_keyword>
      <i_keyword>Control group: Subjects in this group will not receive any additional training or exercise intervention outside of their daily routine and regular soccer team training during the 8-week study period, and will only continue their routine sports activities.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Landing error pattern score. Timepoint: Before the intervention (baseline) and immediately after the intervention (8th week). Method of measurement: Analysis of recorded landing videos based on the Landing Error Scoring System.</prim_outcome>
      <prim_outcome>Lower extremity dynamic balance. Timepoint: Before the intervention (baseline) and immediately after the intervention (8th week). Method of measurement: Measuring the reach distance in different directions using the Lower Quarter Y Balance Test.</prim_outcome>
      <prim_outcome>Lower extremity functional performance in hop tests. Timepoint: Before the intervention (baseline) and immediately after the intervention (8th week). Method of measurement: Recording hop distance or trial time in the single leg triple hop test, lateral hop test, and figure of eight hop test using a tape measure and stopwatch.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Not applicable. Timepoint: Not applicable. Method of measurement: Not applicable.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Payame Noor University</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2021-10-27</approval_date>
        <contact_name>Research Ethics Committees of Payame Noor University</contact_name>
        <contact_address>Payame Noor University, Nakhl St., Artesh Blvd., Tehran, Iran Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
