IRCT201406169014N36 IRCT 2014-06-23 Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences The effect of cerebrolysin versus placebo on improvement of patients with acute ischemic stroke The effect of cerebrolysin versus placebo on improvement of patients with acute ischemic stroke: a double blinded randomized clinical trial 2013-07-23 anticipated 122 Complete https://irct.ir/trial/9475 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: Randomization: A systematic random allocation method is used so that the patients who referred to the first specialist were assigned to the intervention group and the patients who referred to the second specialist were assigned to the control group. Blinding: All patients received the same intravenous treatment with different context. Thus they were unaware of the type of intervention. In addition, the physician who examined the patients was not aware of the intervention. Therefore, the trial was run as double blinded. 2 Ichemic stroke. Intervention 1: Routine treatment of ischemic stroke plus intravenous infusion of cerebrolysin 10 ml in 100 ml normal saline daily for 7 days. Intervention 2: Routine treatment of ischemic stroke plus intravenous infusion of 100 ml normal saline alone daily for 7 days.