IRCT201203089235N1 IRCT 2012-10-16 Tehran university medical scince Determination of mgso4 infusion effect for treatment of patient with acute pulmonary edema arrived rasol and sina hospital from khordad 1391 to khordad 1392 Determination of mgso4 infusion effect for treatment of patient with acute pulmonary edema arrived rasol and sina hospital from khordad 1391 to khordad 1392 2012-06-05 anticipated 40 Complete https://irct.ir/trial/9826 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Single, Purpose: Treatment. N/A Acute pulmonary edema. Intervention 1: In intervention group start treatment by o2 until o2Sat of patient >94% (minimum by 4 lit/min o2),plus Amp lasix 1 mgr/kg and Amp nitroglycerin 5 mic gr/min started and titrated 5 mic gr/min if patients blood pressure permitted, and Amp morphine sulfate 0.05 mgr/kg for attention of patient blood pressure (preferly systolic blood pressure> 90 mmhg).these treatment are basic treatment of acute pulmonary edema. in addition to in intervention group gives 1 gr Mgso4 in 100 cc normal saline for 20 min. Intervention 2: In control group start treatment by o2 until o2Sat of patient >94% (minimum by 4 lit/min o2),Amp lasix 1 mgr/kg and Amp nitroglycerin by 5 mi cgr/min started and titrated 5 mi cgr/min if patients blood pressure permitted, and Amp morphine sulfate 0.05 mgr/kg for attention of patient blood pressure (preferly systolic blood pressure> 90 mm hg).these treatment are basic treatment of acute pulmonary edema.but in control group we administrate basic treatment of acute pulmonary edema and not infused Mgso4. as we administrate 100 cc normal saline in 20 min for placebo instead Mgso4.