The aim of this study is comparison of exposure and occlusive dressing in reduction of recovery time. For this purpose, 100 patients treated with occlusive and 100 with exposure dressing. In exposure dressing the burn wounds cleaned and necrotic tissues was removed, then washed with baby shampoo followed by normal saline solution. After that, the wounds were dried with sterile gauze and covered with silver sulfadiazine cream in depth 16 millimeter. In next day same procedure was repeated, and during the first week of treatment sample was taken from the wound before dressing and transferred to transport medium for the culture. In occlusive after the treatment wounds would be covered with sterile gauze. The following day and during the first week of dress changing before dressing samples were taken from wounds and inoculated into transfer media for the culturing in the laboratory .This process will be continued until complete recovery. Inclusion criteria for this study are as follow:
Burn out-patients
And the exclusion criteria are as follow:
Burn out-patients with not more than2 degree of burning and not taken cephalexin antibiotic.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2012071110245N1
Registration date:2012-12-31, 1391/10/11
Registration timing:prospective
Last update:
Update count:0
Registration date
2012-12-31, 1391/10/11
Registrant information
Name
Mohammad Kazem Sharifi-Yazdi
Name of organization / entity
Tehran University of Medical Sciences, School of Allied Siences,Tehran, Iran
Country
Iran (Islamic Republic of)
Phone
+98 21 8670 4777
Email address
mksharifi@tums.ac.ir
Recruitment status
Recruitment complete
Funding source
Tehran University of Medical Sciences (TUMS)
Expected recruitment start date
2013-02-20, 1391/12/02
Expected recruitment end date
2014-02-21, 1392/12/02
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of occlusive and exposure dressing in burn infectious control in order to reduce time for the treatment and return to normal life.
Public title
dressing for the burn infectious control
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria
Burn out-patients
Exclusion criteria
Burn out-patients with not more than2 degree of burning and not taken cephalexin antibiotic
Age
No age limit
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
100
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Tehran University of Medical Sciences Ethics Committee
Street address
Tehran University of Medical Sciences, Keshavarz blv.
City
Tehran
Postal code
Approval date
2012-03-20, 1391/01/01
Ethics committee reference number
59061
Health conditions studied
1
Description of health condition studied
Burn
ICD-10 code
T20-25
ICD-10 code description
Burns and corrosions of external body surface
Primary outcomes
1
Description
infection
Timepoint
after intervention
Method of measurement
visual
Secondary outcomes
1
Description
Treament period
Timepoint
cure period
Method of measurement
ocular
Intervention groups
1
Description
In exposure dressing the burn wounds cleaned and necrotic tissues was removed, then washed with baby shampoo followed by normal saline solution. After that, the wounds were dried with sterile gauze and covered with silver sulfadiazine cream in depth 16 millimeter. In next day same procedure was repeated, and during the first week of treatment sample was taken from the wound before dressing and transferred to transport medium for the culture
Category
Treatment - Drugs
2
Description
In occlusive dressing after the treatment wounds would be covered with sterile gauze. The following day and during the first week of dress changing before dressing samples were taken from wounds and inoculated into transfer media for the culturing in the laboratory .This process will be continued until complete recovery.
.
Category
Treatment - Drugs
Recruitment centers
1
Recruitment center
Name of recruitment center
Emergency department, Motahari Burn Hospital
Full name of responsible person
Dr mohammad mehdi soltan dallal
Street address
City
Tehran
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Tehran university of medical sciences
Full name of responsible person
vice chancellor for research
Street address
bolvar keshavarz,khods ave
City
tehran
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Tehran university of medical sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
school of public health,tehran university of medical sciences
Full name of responsible person
Dr mohammad mehdei soltan dallal
Position
professor,Phd,head of microbiology division
Other areas of specialty/work
Street address
bolvar keshavarz,khods aven
City
tehran
Postal code
Phone
+98 21 8899 2971
Fax
Email
soltanirad34@yahoo.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Tehran university of medical sciences
Full name of responsible person
Dr mohammad mehdi soltan dallal
Position
head of microbiology department,scool of public health,tehran university of medical sciences
Other areas of specialty/work
Street address
bolvar keshavarz,khods ave
City
tehran
Postal code
Phone
+98 21 8899 2971
Fax
Email
soltanirad34@yahoo.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
scool of public health,tehran university of medical sciences
Full name of responsible person
dr mohammad mehdi soltan dallal
Position
head of microbilogy division,Phd
Other areas of specialty/work
Street address
bolvar keshavarz,khods ave
City
tehran
Postal code
Phone
+98 21 8899 2971
Fax
Email
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)