Effect of dual task training on somatosensory, balance, activity of daily living and Community participation in patient with relapsing-remitting Multiple sclerosis: Double Blind Clinical Trial

Effect of cognitive-motor dual task training on somatosensory, balance, activity of daily living and community integration in patient with relapsing-remitting Multiple sclerosis

A prospective study of a blind clinical trial with two parallel, randomized groups

The samples are selected from the clients of the Multiple Sclerosis Society of Isfahan and randomly divided into two groups. Before the randomization, patients are described, which will be divided into two groups with two different programs. After obtaining patient consent and collecting demographic data, EDSS will be used to diagnose patients' incapacity. Clients, the person who evaluates, and the person who performs the rehab program do not know the type of group (intervention, control).

Inclusion criteria: diagnosis of multiple sclerosis, EDSS 2-5/5, Ability to stand without any support, Having a sensory problem on the soles of the foot ,Remitting during the last 30 days, Having the ability to read and write, The doctor confirmed to participate in research Exclusion criteria: People with diseases such as diabetes, epilepsy and with any problem in the musculo-skeletal system: History of surgery, History of fractures, and ... that disturbs the balance, Receive corticosteroid treatment one month before the study, MMSE-less than 24, Uncorrected visual disorders, Relapsing, Inability to walk a distance of 25 feet with or without assistive device

Intervention group: cognitive-motor dual task training control group: balance training

Intervention(cognitive-motor dual task training): independent variable Somatosensory: dependent variable Balance: dependent Community integration: dependent Instrumental activity of daily living: dependent Activity of daily living: dependent

Method: Restricted Randomization by random allocation rule method: first, a sample size determine and then randomly assign a set of them to Group A and assign the remainder to Group B. Random unit: Individual Non-transparent envelopes are used to hide random assignments In this method, first, a random sequence is created using the above method. Then, based on the sample size of the research, a number of envelopes with an aluminum wrapper (in order to avoid the clarity of the contents of the envelopes) are prepared and each random sequence created on a card is recorded and the cards is placed inside the envelopes. At the time of the start of the registration of the participants, one of the envelopes shall be opened in accordance with the order of entry of the eligible participants, and the group allocated to that participant shall be revealed. Process execution:One person will create a random sequence, the other will examine the participants in terms of inclusion and exclusion criteria and enroll them in the study, and the third person will assign the participants to the groups.

The participant will be notified in two groups whose programs are different. Practitioners who train the intervention program do not know about the intervention and control group program.