The comparative Evaluation of Efficacy of intravenous lidocaine 2% and propofol in preventing laryngospasm and complications after tonsilectomy

The comparative Evaluation of Efficacy of intravenous lidocaine 2% and propofol in preventing laryngospasm and complications after tonsilectomy

102 children aged 3-14 years admitted for adenotonsillectomy randomly assigned into 5 blocks in a randomized, double blind randomized clinical trial, in one of the two intravenous administration of lidocaine 2% and propofol.

In this study, children aged 3 to 14 years were candidates for adenotonsillectomy who will be referred to the Fatemiyeh Hospital of Hamedan during the study period, will be randomly assigned to randomized allocation blocks by random sampling.

Inclusin Criteria: Aged 3-14 years old; Candidate for elective adenotonsilectomy; Parental Satisfaction Exclusion Criteria: Those who are reluctant to continue to participate in the study; History of Cardio-pulmonary disease; Recent infection of the upper respiratory tract and febrile illnesses; History of allergy to eggs, soy, lidocaine and propofol; difficult intubation; Corticosteroid use

Intervention group 1: Children aged 3 to 14 years old are candidates for adenotonsillectomy, which will receive 2 mg / kg Lidocaine for two minutes prior to extubation. Intervention group 2: Children aged 3 to 14 years old are candidates for adenotonsillectomy, which will receive propofol 0.5 mg / kg for two minutes prior to extubation.

Laryngospasm

we provide ten paper sheets . We write five letters A and on five other sheets of letter B. We mix the papers together and put them in the drawer of the table.With each of the qualified patients, one of the papers is taken out randomly and, According to the text, the patient is given one of two groups: A (Propofol) and B (Lidocaine). Then, for ten subsequent patients, the paper is returned to the bag again, and this process is repeated until the end of the sample volume.

In both groups A and B, medications (propofol or lidocaine) will be prescribed two minutes before the extubation of the chip. In order to prevent the medication being detectable for patients and investigators, they are prepared and injected into syringes of the same size and shape and on the adhesives A and B by the anesthetist. Since drugs are prescribed and prescribed by an anesthetist, the clinician will not be aware of the type of prescribed medication that will measure and record the outcome of the study.