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Study aim
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Determine the effect of Ondansetron injection before NG-Tube on the severity of pain, discomfort and nausea and vomiting caused by NG-Tube.
Determine the effect of Metoclopramide injection before NG-Tube on the severity of pain,discomfort and nausea and vomiting caused by NG-Tube.
Comparison of the effect of intravenous Metoclopramide and Ondansetron on the severity of pain,discomfort and nausea and vomiting caused by NG-Tube.
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Design
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A randomized, double-blind, placebo-controlled clinical trial
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Settings and conduct
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The study is performed in the hospital emergency department, in patients who require NG tube. Patients were randomly divided into ondansetron, metoclopramide and placebo groups.The project associate will label the syringes without the knowledge of the researcher, physician, nurse, and patient evaluator, and all NG tube insertions will be performed by a person who is unaware of the placement into groups. The degree of discomfort, the severity of pain and nausea will be assessed immediately,30 and 60 minutes after the procedure using the VAS criteria.
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Participants/Inclusion and exclusion criteria
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Patients with an indication of NG tube and over 18 years old who are willing to participate in the study are included. Patients with unconsciousness; pregnancy; unstable hemodynamic status; nasal bleeding; nasal anatomical problems; sensitivity to metoclopramide and ondansetron; use of metoclopramide and ondansetron interfering drugs; patients presenting with nausea and vomiting; trauma patients and patients have more than twice attempted a NGT insertion Yard is not included in the study.
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Intervention groups
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For the group1, 10 mg ondansetron and for the group2, 10 mg metoclopramide administered intravenously 15 minutes before the procedure, and for the control group, the same volume of normal saline administered.
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Main outcome variables
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Discomfort; severity of pain; nausea