For randomization, the permuted balanced blocks method was used. In this method, six balanced blocks (1 to 6) were defined regarding the three interventions of the study (A, B, C) including BAC, ACB, ABC, CAB, BCA and CBA . The patients were divided into 49 groups of three patients. The patients’ numbers were inserted from 1 to 147 in a column using MS Excel software. In another column, the group of each patient was inserted, for example: patients 1 to 3 as group 1, patients 4 to 6 as group 2, …, patients 144 to 147 as group 49. In another Excel sheath, the groups were inserted from 1 to 49, and the blocks were inserted across each group from 1 to 6 in order till the end. In the next column, non-repeated random numbers were inserted using the “RANDL()” command. Subsequently, the order of the blocks was randomly changed. According to the block assigned with each group, the intervention regarding each patient was determined. For example, if group 1 is assigned with “CAB”, the interventions were as follows: Patient 1, C; Patient 2, A; Patient 3, B.