Evaluation of the effect of tissue adhesive and suture techniques on the postoperative pain after the tooth extraction

 Evaluation the effect of tissue adhesive and suture techniques on the postoperative pain after the tooth extraction

The clinical trial consisted of two randomized double-blind parallel groups on 18 patients. Random allocation Software version 1 was used for randomization.

At Yazd school of dentistry, either the left or right premolar will be randomly extracted by a surgical resident, then it will be sutured using 3.0 Silk thread (Supasil Co., made in Iran). In order to measure the pain intensity after the surgery, each patient will be given a visual analogue scale (VAS) form to complete. The patient will be asked to record their pain intensity on a chart at 5, 12, 24 and 48 hours after the tooth extraction. After two weeks, the patient will be required to attend the school for following steps of the treatment. The patient’s first premolar on the other side will be extracted by the resident and the silent tooth will be covered with mucous adhesive. The VAS form will be returned to the patient to record their pain intensity 5, 12, 24 and 48 hours later.

Inclusion criteria : People without systemic disease - No history of allergic to any drugs - With good oral hygiene. At first written consent will be obtained from the patient. Exclusion criteria: Fear of dentistry

Intervention group 1:Mucosal adhesive Intervention group 2:Suture

Pain intensity is the main variable which will be measured based on the Visual Analogue Scale at 5-12-24 and 48 hours after tooth extraction.

In this study, 18 qualified patients will be selected. For each patient, the first premolars will be extracted in the first session and the first premolars on the opposite side of the same jaw will be extracted in the second session and additionally the wound will be covered with sutures or mucosal adhesive. All the patients will be numbered (1 to 18). First, using Random allocation software version 1 and block random allocation method, we will determine the random sequence for numbers 1 to 18. For each number, either the mucosal adhesive (A) or sutures (B) interventions will be applied either in the first turn or in the second turn. Totally, 18 pair blocks (an A&B pair block for each patient) will be identified. In order to blind the random allocation, the random allocation list will be given a third party who knows nothing about the interventions and will be asked on the phone to choose intervention A or B for the patient.

In order to blind the study in both directions, the patient and the statistical consultant will not know which side of the tooth is pulled at each stage and which technique is used to cover the wound.