The effect of high intensity interval resistance training and vitamin D intake on the levels of Sirtuin1, Eotaxin-1 and some anti inflammatory-oxidative markers in overweight women with low vitamin D status.

Evaluate the effect of intense interval resistance and running training with vitaminD intake on the levels of sirtoin1, eutoxin-1 and some anti-inflammatory-oxidative markers in overweight women with low vitaminD status.

This study is a quasi-experimental one-blind clinical trial that will be performed using a pre-post test design with a control group for 8 weeks. Subjects were randomly divided into six groups: control, vitaminD, resistance interval, running interval, resistance interval+vitaminD and running interval+vitaminD. Exercise or combinations with vitaminD groups perform the prescribed exercises. VitaminD and exercise+vitaminD groups will receive 50,000IU of VitaminD weekly.

The statistical population includes sedentry women with body mass index between 25-29kg/m2, referred to Babol sports clubs. High intensity interval resistance and/or running training are performed three sessions per week for 8 weeks at the Paya Sports Club in Babol. Subjects in the vitaminD or combination groups, and the exercises or control groups, will take supplement and placebo, respectively.

Inclusion criteria: Being overweight, being a non-athlete, having levels of 25-hydroxyvitaminD less than 30ng/ml .Exclusion critiaer: Smoking, use of special drugs, use of any supplements.

The training groups performs high intensity interval resistance (with an intensity of 70% of 1RM) and/or running (12x1-min running bouts at 80-90% HRmax) trainig for 8 weeks.The supplement group will take 50,000IU of vitaminD capsules weekly for 8 weeks .Supplemental+training groups, in addition to performing the desired exercises, similar to the supplement group, take vitaminD. The control group does not undergo intervention.

Siirtoin1, eutoxin-1,Inflammatory and anti-inflammatory markers, antioxidant markers

Add study on the effect of high-intensity interval running exercises, in addition to studying the effect of high-intensity resistance training exercises and comparing the effect of these two types of exercises on the studied variables(Due to the commonality of control and Supplement groups)

At first, the subjects will be selected using a simple random method. Then, using a table of random numbers, they are divided into six groups: control, resistance interval, running interval, vitamin D, resistance interval+vitamin D and running interval+ vitamin D. Therefore, each of the candidates will be assigned a two-digit number from 01, 02, …, 10, 11, …, to 52. The same number of digits is determined for the selection of individuals by starting a hand movement from a point in the table of random numbers in the direction of the desired row or column (five-digit numbers whose last two digits are similar to the existing codes) and each is randomly assigned to One of the groups. This will continue until the number of people in each group is completed. Therefore, the researcher will not have the option to change the status of the assignment or predict it. Random disguise will be done by a third party who does not participate in other stages of the intervention.

Analysts will be blind. The researcher will administer vitamin D capsules (50,000 units) to vitamin D, resistance interval+ vitamin D, running interval+ vitamin D individuals as well as placebo to control and exercise groups

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