Comparison of the effect of Nettle and Alyssum with Q10 plus and L-Carnitine on improving sperm parameters of infertile men referred to infertility clinic

Comparison of the effect of Nettle and Alyssum with Q10 plus and L-Carnitine on improving sperm parameters of infertile men referred to infertility clinic in Jahrom city, 2021.

A randomized controlled clinical trial with parallel groups, three blinded, randomized

The researcher, after approving the project in the Research Council of Rafsanjan University of Medical Sciences and obtaining the code of ethics and obtaining the necessary authorization to conduct research, will refer to the infertility clinic in Jahrom city . Male infertility are screened for entry requirements and if eligible, explaining the purpose of the study, they are invited to participate in the project and they will enter the study with written consent. To the intervention group orthidine tablets 150 mg, 3 daily and extract of Qadoomeh, 2 capsules of 300 mg daily and The control group will be given KQ10 Plus 100 mg and L-carnitine 500 mg daily For 12 weeks. T the study will be three-blind.

Inclusion criteria: Willingness to participate in the study and written consent, Living with a spouse, Spouse un infertility, Age 20 to 45 years, Disorder in at least one of the sperm parameters Infertility after 12 months of intercourse without using contraceptive methods,

Intervention group: Intervention group: Taking orthidine tablets 150 mg, 3 daily and extract of Alyssum, 2 capsules of 300 mg daily and Control group: Qu10 Plus 100 mg tablets and L-carnitine 500 mg tablets daily For 12 weeks

Status of spermogram parameters, before and 12 weeks after the start of the intervention

In this study, we use a random number table to assign infertile men to the control and intervention groups. The table of random numbers consists of random digits 0 to 9 And each of the digits in this table is repeated the same on average And there is no pattern of recognizable numbers. We make a random list using the random digits in the table, assigning each digit to a therapeutic appointment. Now for the two treatments, we assign the numbers 4-0 for treatment A and the numbers 5-9 for treatment B. We start the list at an optional point in the table that we have chosen at random. For example, if we start from the top row of the random number table randomly and optionally and And from left to right of the table and then move to the bottom rows, they create a list Which begins with the following treatments. We will continue to do this until our sample is complete.

The meaning of the three blinds is that the participants (people qualified to enter the project)، Assessor (the person who is to complete the relevant checklist before and 12 weeks after treatment) And Data Analyzer (Statistics Specialist) Unaware of which group (intervention or control) the information received and statistical data belong to.