The aim of this study is to investigate the effects of eight weeks circuit resistance training on some inflammatory and endothelial markers in pre-hypertensive obese women
Design
The study have1 control and 1 intervention group, on 24 pre-hypertension women, Randomization is done by lottery using the list of volunteer's names.
Settings and conduct
Gym bodybuilding, private section, Kermanshah
Participants/Inclusion and exclusion criteria
The subjects must be obese. and pre-hypertensive. They must have no diseases or skeletal problem. They dont use any medicine or diets.
Intervention groups
Circuit resistance training group, Control group
Main outcome variables
Anthropometric variables (body mass index, waist-to-hip ratio, body fat percentage, weight);
Blood pressure variables (systolic and diastolic blood pressure);
Insulin Resistance Variable;
Inflammatory variables (interleukin-1 beta, tumor necrosis factor alpha); Endothelial-related variables (endothelial-1 and nitric oxide).
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20210824052279N1
Registration date:2021-08-31, 1400/06/09
Registration timing:prospective
Last update:2021-08-31, 1400/06/09
Update count:0
Registration date
2021-08-31, 1400/06/09
Registrant information
Name
Hengameh Moradian
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 83 3721 2165
Email address
hengameh.moradiyan@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2021-09-01, 1400/06/10
Expected recruitment end date
2021-11-01, 1400/08/10
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The Effects of 8 Weeks of Circuit Resistance Training on Some Inflammatory and Endothelial Markers in Pre-hypertensive Obese Women
Public title
The Effects of 8 Weeks of Circuit Resistance Training on Some Inflammatory and Endothelial Markers in Pre-hypertensive Obese Women
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
They should be obese (BMI>,30).
Their blood pressure must be about 120-139 and 80-89 mmHg.
Exclusion criteria:
Subjects have any special disease or skeletal problems.
They use weight loss medication or diet.
Age
From 40 years old to 50 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
24
Randomization (investigator's opinion)
Randomized
Randomization description
The researcher gives a special code or number to each member of the community. He then writes down the number of each of them on a small piece of paper or cardboard; then puts them into a box or container and mixes them. Then he takes out the cards one by one, writes down their number, and continues to do so until he chooses 24 numbers. When the number of samples is completed. The same method is used to determine the control and intervention groups. In this way, a number from 1 to 24 is assigned to participants, then writes on cards and puts in a bag. The first 12 numbers that are took out of the bag is assigned to the control group and the next 12 numbers to intervention group.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics Committee of The Institute of Physical Education
Street address
Sharyati street
City
Kermanshah
Province
Kermanshah
Postal code
6713986161
Approval date
2021-07-18, 1400/04/27
Ethics committee reference number
IR.SSRC.REC.1400.069
Health conditions studied
1
Description of health condition studied
pre-hypertension
ICD-10 code
I10
ICD-10 code description
Essential (primary) hypertension
Primary outcomes
1
Description
blood pressure
Timepoint
48 hours before and after intervention
Method of measurement
Barometer, Beurer, Germany
2
Description
Anthropometric profiles
Timepoint
48 hours before and after intervention
Method of measurement
Skinfold Caliper, Harpenden, UK- meter
3
Description
Lipid profiles (Triglyceride, Cholesterol, Low density lipoprotein, High density lipoprotein)
Timepoint
48 hours before and after intervention
Method of measurement
Blood sampling, Pars azmoon kit, Tehran, Iran
4
Description
Insulin resistance
Timepoint
48 hours before and after intervention
Method of measurement
Blood sampling using fasting glucose and insulin, Mercodia kit, Iceland, Sweden.
Intervention group: CRT group will perform circuit resistance training for 8 weeks which according to the recommendations of the American Heart Association will be 40% 1RM for upper body and 60% 1RM for lower body movements.The training protocol is for 8 weeks, 3 sessions per week and each session is 50 to 60 minutes (15 minutes of warm-up, 30 minutes of weight training, 10 minutes of cooling). Resistance movements performs in the form of 3 circles and 9 stations, including four upper body movements (chest press, lat pull down, seated cable row, biceps cable curl) and three lower body movements (leg press, seated leg extension, leg curl), and two core-body movements (crunch and back extension) . The order of performing the movements is such that first the mid-torso movements and then the upper and lower torso movements are performed alternately.
Category
Rehabilitation
2
Description
Control group: All measurements will be performed like the intervention group 48 hours before and after the intervention, except that they will not have physical training during 8 weeks.
Category
Rehabilitation
Recruitment centers
1
Recruitment center
Name of recruitment center
Recall Notice
Full name of responsible person
Hengameh Moradian
Street address
Sharyati street
City
Kermanshah
Province
Kermanshah
Postal code
6713986161
Phone
+98 83 3721 2165
Email
hengameh.moradiyan@gmail.com
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Islamic Azad University
Full name of responsible person
Hengameh Moradian
Street address
Kasra street
City
Kermanshah
Province
Kermanshah
Postal code
6718997551
Phone
+98 83 3724 3181
Email
hengameh.moradiyan@gmail.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Islamic Azad University
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic
Person responsible for general inquiries
Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Hengameh Moradian
Position
PH.D student
Latest degree
Master
Other areas of specialty/work
Exercise physiology
Street address
Sharyati street, Moradian apartment
City
Kermanshah
Province
Kermanshah
Postal code
6713986161
Phone
+98 83 3721 2165
Email
hengameh.moradiyan@gmail.com
Person responsible for scientific inquiries
Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Hengameh Moradian
Position
Student
Latest degree
Master
Other areas of specialty/work
Others
Street address
Sharyati
City
Kermanshah
Province
Kermanshah
Postal code
6713986161
Phone
+98 83 3721 2165
Fax
Email
hengameh.moradiyan@gmail.com
Person responsible for updating data
Contact
Name of organization / entity
Islamic Azad University
Full name of responsible person
Hengameh Moradian
Position
Phd Student
Latest degree
Master
Other areas of specialty/work
Others
Street address
Sharyati
City
Kermanshah
Province
Kermanshah
Postal code
6713986161
Phone
+98 83 3721 2165
Fax
Email
hengameh.moradiyan@gmail.com
Sharing plan
Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Not applicable
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
No - There is not a plan to make this available
Data Dictionary
No - There is not a plan to make this available
Title and more details about the data/document
Total potential data can be shared after people are identifiable
When the data will become available and for how long
Start access period after printing results
To whom data/document is available
public
Under which criteria data/document could be used
Using the considered training intensity
From where data/document is obtainable
hengameh.moradiyan@gmail.com
What processes are involved for a request to access data/document