The effectiveness of computer-based cognitive rehabilitation therapy in improving memory, attention and executive function of patients with dementia after stroke

The effect of computer-based cognitive restoration on improving memory, attention and executive function in patients with dementia

This study was performed as a clinical trial with parallel and randomized groups on 30 patients with dementia due to stroke and these patients were randomly divided into two groups of education and control.

First, patients who meet the inclusion criteria will be examined and randomly assigned to the control and experimental groups, and then cognitive rehabilitation will be performed in 15 sessions of 30 minutes at the Baghcheban Cognitive Rehabilitation Clinic in Arak for the experimental group. Finally, the two groups will be evaluated for dependent outcomes.

inclusion criteria : Patients with dementia who have had a stroke for at least 3 months , age 30-70 years old Non-entry criteria : Having diabetes , Cerebral venous thrombosis , Head and neck injuries , History of chronic heart failure with EF less than 30% , History of dementia medications

Intervention group: The protocol of cognitive rehabilitation intervention using a computer includes training on the functions of continuous attention, selective attention, focused attention, continuous attention, response inhibition, and short-term memory in each session, respectively. The number of cognitive rehabilitation sessions is 20 30-minute sessions twice a week. This protocol is based on Sulberg & Matter's (2004) Attention Processing Training Protocol. Control group: No educational intervention.

n order to perform pre-test and post-test for the "attention" variable, continuous and simple stropping tests will be used, for the "memory" variable, MoCA and MMSE, and for the "executive performance" variable, the Wisconsin test will be used.

Participants are assigned to two intervention and control groups, respectively, based on the randomization sequence that will be generated beforehand. This sequence is unpredictable and its arrangement is completely random. Block randomization method with 8 blocks will be used to allocate samples. Thus, using block numerical random number generation software, a randomization sequence proportional to the sample size required for the two groups will be generated. Initially, all cases in which the two letters A and B can be arranged in blocks of 8 are produced. A block is then randomly selected from the blocks and the layout pattern in that block will be used to assign participants. This block will then be placed in the main container and another block will be selected again. All this will be done with software called Sealed Envelope. With this method, concealment will also be observed. The concept of concealment is to unpredictably assign individuals to groups. In fact, the researcher will not be able to predict which group the next person will be in.

After conducting this study and analytical studies on it, only a part of the data such as information about the main outcome and patient demographic information will be published to the researchers who do the necessary correspondence with the person in charge of this study.

Access will be from 2022/4/20 to 2026/4/20 for 4 years.

University researchers

If there are any further questions

Dr Mostafa Nokani

Letter writing should be done with professors and universities.