-
Study aim
-
Determining the effectiveness, safety, tolerability and satisfaction of electrosurgery and cryosurgery in patients with sebaceous hyperplasia, seborrheic keratosis, cherry angioma and skin tag
-
Design
-
Clinical trial with two intervention groups, parallel, randomized, phase 2-3 on 128 patients, randomized with sealed envelopes
-
Settings and conduct
-
Each lesion is randomly assigned to one of the following two treatment groups: group a: electrosurgery and group b: cryosurgery. For lesions of the first group, electrosurgery is repeated 4 weeks later if necessary and for group b lesions, cryosurgery is repeated 2 and 4 weeks later if necessary. In order to follow up, patients in both groups, 2 weeks, 1 month and also 3 months after the initial session are visited and The data are evaluated by the patient himself, a blind dermatologist and finally the statistical specialist. Also, safety, tolerability and satisfaction of treatments are questioned in follow-up sessions.
-
Participants/Inclusion and exclusion criteria
-
Inclusion criteria:
confirmation of diagnosis with a clinical examination by a dermatologist, age 18 to 70 years
Exclusion criteria:
For both treatments: infection of the lesion site, history of keloid, pregnancy and lactation, malignancy, immunosuppression
For electrosurgery: having an intracardiac device
For cryosurgery: cold intolerance, history of Raynaud's phenomenon, vesiculobullous diseases and superficial sensory involvement
-
Intervention groups
-
group 1: Electrosurgery
group 2: Cryosurgery
-
Main outcome variables
-
The rate of improvement, Lesion size