Comparative effect of the mouthwash containing propolis-aloe vera plant extract and chlorhexidine solution on plaque and gingival bleeding indexes in Generalized marginal gingivitis patients.

Comparison of the effect of mouthwash containing propolis- Aloe vera herbal extract and Chlorhexidine solution on plaque index and gingival bleeding in people with generalized marginal gingivitis.

A single blind clinical trial with two intervention groups and one control group on 60 patients.

60 people who refer to the Research Center of Tabriz University of Medical Sciences are randomly assigned to one of 3 groups in a single-blind manner. After primary recording indexes they receive a coded bottle of mouthwash from the nurse . The patients are told to use the mouthwashes twice a day for two weeks. After the end of the second week, the patients are called and the gingival, plaque and bleeding index during probing are recorded and the information is subjected to statistical analysis.

Inclusion criteria: Suffering from generalized marginal gingivitis, have not received antibiotics in the past 6 months . Not committed systemic diseases that causes generalized gingivitis. Not suffering periodontitis. Exclusion criteria : Patients with cardiovascular diseases and diabetes. Patients who smoke, have chronic or acute infections.

Intervention group 1: using BEHSA 0.2% chlorhexidine mouthwash for 14 days, 10 ml twice a day After brushing teeth and not eating or drinking for half an hour. intervention group 2: use of aloe vera propolis mouthwash Water based 50 percent (formulated in Tabriz Faculty of Pharmacy)10 ml twice a day for 14 days After brushing teeth and not eating or drinking for half an hour.control group: using NIKOO SHIMI distilled water as a mouthwash for 14 days twice a day 10 ml After brushing teeth and not eating or drinking for half an hour

Plaque index in probing, bleeding in probing, Depth of envelope in probing

In this study, the permutation block method will be used to randomly assign patients to the studied treatment groups. For this purpose, 20 blocks of three will be created including the studied treatments, in each block a random sequence of A, B, C will be created. The blocks will be randomly selected and based on the sequence in each group of patients, they will be assigned to 3 treatment groups from the beginning of the list of patients. To create a random sequence, a table of random numbers will be used.