The aim of this study will determine the effect of tomato juice consumption as a rich source of lycopene (a potent antioxidant) on inflammatory biomarkers of male athletes following exhaustive exercise. And study design will be Control Clinical Trial.
In this study 30 male university students will enroll and randomly divide into two groups. The experimental group will consume 200 mL tomato juice daily (containing 50 mg of lycopene) for one week, and then performed exercise on treadmill at a speed of 18 km/hour till exhaustion. The control group will consume the same amount of water and will perform the same exercise regimen. Blood samples will collect pre- and immediately post-exercise for analysis of IL-6, CRP and oxidant/antioxidant ratio.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT201301166415N5
Registration date:2014-12-18, 1393/09/27
Registration timing:retrospective
Last update:
Update count:0
Registration date
2014-12-18, 1393/09/27
Registrant information
Name
Ahmad Saedi Some Olia
Name of organization / entity
Tehran University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 6640 2095
Email address
a_saedi@sina.tums.ac.ir
Recruitment status
Recruitment complete
Funding source
Investigator
Expected recruitment start date
2009-05-10, 1388/02/20
Expected recruitment end date
2009-05-17, 1388/02/27
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of tomato juice consumption on the inflammatory biomarkers of male athletes following exhaustive exercise
Public title
Effect of tomato juice on inflammatory bio-markers in exhaustive exercise
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria: Healthy Exercise Student Volunteer of University of Tehran Exclusion criteria: Unhealthy Exercise Student Volunteer of University of Tehran
Age
From 19 years old to 21 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
30
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Faculty of Sport Science and Physical Activity, University of Tehran
Street address
15th- Amirabad Shomali ( Kargar)Ave,
City
Tehran
Postal code
Approval date
2009-01-03, 1387/10/14
Ethics committee reference number
11250
Health conditions studied
1
Description of health condition studied
Inflammation
ICD-10 code
D80-D89
ICD-10 code description
Certain disorders involving the immune mechanism
Primary outcomes
1
Description
Supplementation by Tomato Juice (Decreased Inflammation)
Timepoint
One Week
Method of measurement
Measurement of Inflammtion Biomarker (IL-6, CRP, Oxidant/Antioxidant)
Secondary outcomes
empty
Intervention groups
1
Description
Thirty male sport students will enroll and randomly divide into two groups. The experimental group will consume 200 mL tomato juice daily (containing 50 mg of lycopene) for one week, and then will perform exercise on treadmill at a speed of 18 km/hour till exhaustion. Blood samples will collect pre- and immediately post-exercise for analysis of IL-6, CRP and oxidant/antioxidant ratio.
Category
Other
2
Description
Thirty male sport students will enroll and randomly divide into two groups. The experimental group will consume 200 mL water daily for one week, and then will perform exercise on treadmill at a speed of 18 km/hour till exhaustion. Blood samples will collect pre- and immediately post-exercise for analysis of IL-6, CRP and oxidant/antioxidant ratio.
Category
Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Student of Sport Science of Faccalty of Sport Science, University of Tehran
Full name of responsible person
Street address
15 th, Amir Abad Ave,
City
Tehran
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Investigator
Full name of responsible person
Mohammad Taherireykande
Street address
Clinic of University of Tehran,16 Azar, Enghelab Ave,
City
Tehran
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Investigator
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Department of Cellular & Molecular Nutrition, School of Nutrition and Dietetics, Tehran University o
Full name of responsible person
Dr. Ahmad Saedi Some Olia
Position
Assistant Professor
Other areas of specialty/work
Street address
Keshavarz Blv.
City
Tehran
Postal code
Phone
+98 21 8895 5742
Fax
Email
a_saedi@tums.ac.ir
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Department of Cellular & Molecular Nutrition, School of Nutrition and Dietetics, Tehran University o
Full name of responsible person
Dr. Ahmad Saedi Some Olia
Position
Assistant Professor
Other areas of specialty/work
Street address
Keshavarz Blv.
City
Tehran
Postal code
Phone
+98 21 8895 5742
Fax
Email
a_saedi@tums.ut.ac.ir
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Department of Cellular & Molecular Nutrition, School of Nutrition and Dietetics, Tehran University o
Full name of responsible person
Dr. Ahmad Saedi Some Olia
Position
Assistant Professor
Other areas of specialty/work
Street address
Keshavarz Blv.
City
Tehran
Postal code
Phone
+98 21 8895 5742
Fax
Email
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)