Investigating the effect of carrot (Daucus carota) seed capsules on the sexual desire of female patients with multiple sclerosis

Investigating the effect of carrot (Daucus carota) seed capsules on the sexual desire of female patients with multiple sclerosis

Phase 2 randomized double-blinded placebo parallel clinical trial on 40 patients Randomization using Randomaization.com

Ghaeem hospital MS clinic

Inclusion criteria: Married women; suffering from multiple sclerosis; Age between 18-45 years; complaining of lack or absence of sexual desire; more than 6 months have passed since their marriage; Normal pelvic examination findings; Have a normal pap smear in the past 3 years; Have access to having sex with a partner monthly for at least 15 days. Exclusion criteria: Pregnancy or breastfeeding; Menopause; Disability or serious medical problem that requires constant care and treatment; Suffering from major depressive disorder and other psychiatric disorders; Husband's sexual problems; Divorce.

Intervention group: Women suffering from multiple sclerosis who use 500 mg capsules containing carrot seed powder 3 times a day for 12 weeks. Placebo group: Women suffering from multiple sclerosis who use placebo capsules similar to carrot seed capsules three times a day for 12 weeks.

The overall score of the FSFI questionnaire, which is evaluated at the beginning of the study and every 4 weeks until the 12th week.

Unfortunately, due to the specific family circumstances of some patients, including the lack of consent of the patients' spouses, as well as changes in the project's clinical specialist colleagues due to immigration, the patient recruitment was not completed on time, and the researchers were forced to extend the sampling period for this project.

The blocked randomization method is used. The volume of each block will be four. Then the list of blocks is written and numbers assigned to them, for example (AABB(1)- BBAA(2)- BABA(3)- BAAB(4)), which will be 10 blocks according to the sample size of 40. Then random numbers between 1 and 10 are selected according to the randomization site Randomaization.com and finally, the treatment allocation list is determined based on the random numbers.

Using sealed envelopes Due to the use of a placebo similar to the intervention treatment, the investigator and the participants will not be informed of the assigned treatment, and the analyst will also be unaware of the assigned treatment for the two groups. Finally, after analyzing the data, the researcher who prepared the packages will reveal codes A and B.