The repeated bout effect of a certain eccentric exercise on soreness indicators of the trained and untrained knee extensor muscles in untrained healthy females
The purpose this study is the evaluation of the repeated bout effect of a certain eccentric exercise on soreness indicators of the trained and untrained knee extensor muscles in untrained healthy females. 28 healthy females with no history of performing eccentric or strengthening exercises in lower extremities are randomly assigned into trained and untrained groups. In trained group participants perform two bouts of maximal eccentric exercise at in same extremity. In untrained group, they perform these two bouts but the first bout will be performed in one leg and the other will be performed in the other untrained extremity. Maximal isometric torques at 30, 60, 90 and 120 degrees of knee flexion, maximal concentric torques at 60 and 180 degree per second velocities, delayed onset muscle soreness, knee range of motion, thigh circumference and electromygraphic activity of vastus medialis, lateralis and rectus femoris parts of quadriceps muscle during isometric contraction will be recorded before, immediately after, 48, 120 hours and 14 days after performing two bouts of eccentric exercises.
General information
Acronym
DOMS
IRCT registration information
IRCT registration number:IRCT201204249553N1
Registration date:2013-02-05, 1391/11/17
Registration timing:registered_while_recruiting
Last update:
Update count:0
Registration date
2013-02-05, 1391/11/17
Registrant information
Name
Mandana Rezaei
Name of organization / entity
Tehran University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 41 1337 9268
Email address
m-rezaeim@razi.tums.ac.ir
Recruitment status
Recruitment complete
Funding source
Physiotherapy PhD dissertation
Tehran University of Medical Sciences
Expected recruitment start date
2012-07-22, 1391/05/01
Expected recruitment end date
2013-04-21, 1392/02/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The repeated bout effect of a certain eccentric exercise on soreness indicators of the trained and untrained knee extensor muscles in untrained healthy females
Public title
The effect of eccentric exercise on DOMS indicators of the knee in healthy females
Purpose
Health service research
Inclusion/Exclusion criteria
Inclusion criteria: Healthy females (18-35 yrs range) in the middle of menstrual cycle
Exclusion criteria: participants who are not familiar with resistance training; with isokinetic or eccentric exercise especially in lower extremities;who are not performed lower extremity resistance training in last year; people with sedentary life style ;extra usage of caffein will exclude from study; no history of pathologies and injuries especially in knee joint structures; Participants who performed lower extremity resistance training exercises with the regular basis and who were athletes; Participants have taken medication or any form of dietary supplementation in the preceding 3 months and using these for the duration of the experimental period.
Age
From 18 years old to 35 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
28
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Tehran University of Medical Sciences
Street address
Tehran Keshavarz Bl. Ghods Av.
City
Tehran
Postal code
Approval date
2012-05-12, 1391/02/23
Ethics committee reference number
2800د130/د/90
Health conditions studied
1
Description of health condition studied
Delayed onset muscle soreness
ICD-10 code
R29.8
ICD-10 code description
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
Primary outcomes
1
Description
maximal knee extensor isometric peak torque
Timepoint
Pre test and post test values of dependent variables are obtained immediately before, immediately, 48 hours, 120 hours and 14 days after the performance of 2 bouts of eccentric exercise
Method of measurement
newton meter
2
Description
concentric peak torque at 60 and 180 degree per second velocities
Timepoint
Pre test and post test values of dependent variables are obtained immediately before, immediately, 48 hours, 120 hours and 14 days after the performance of 2 bouts of eccentric exercise
Method of measurement
newton meter
3
Description
angle of concentric peak torque at 60 and 180 degree per second velocities
Timepoint
Pre test and post test values of dependent variables are obtained immediately before, immediately, 48 hours, 120 hours and 14 days after the performance of 2 bouts of eccentric exercise
Method of measurement
degree
4
Description
electromyograhical activity of vastus medialis part of Q.C muscle
Timepoint
Pre test and post test values of dependent variables are obtained immediately before, immediately, 48 hours, 120 hours and 14 days after the performance of 2 bouts of eccentric exercise
Method of measurement
microvolt
5
Description
electromyograhical activity of vastus lateralis part of Q.C muscle
Timepoint
Pre test and post test values of dependent variables are obtained immediately before, immediately, 48 hours, 120 hours and 14 days after the performance of 2 bouts of eccentric exercise
Method of measurement
microvolt
6
Description
electromyograhical activity of rectus femoris part of Q.C muscle
Timepoint
Pre test and post test values of dependent variables are obtained immediately before, immediately, 48 hours, 120 hours and 14 days after the performance of 2 bouts of eccentric exercise
Method of measurement
microvolt
7
Description
delayed onset muscle soreness intensity
Timepoint
Pre test and post test values of dependent variables are obtained immediately before, immediately, 48 hours, 120 hours and 14 days after the performance of 2 bouts of eccentric exercise
Method of measurement
visual analog scale
8
Description
pain pressure threshold
Timepoint
Pre test and post test values of dependent variables are obtained immediately before, immediately, 48 hours, 120 hours and 14 days after the performance of 2 bouts of eccentric exercise
Method of measurement
milimeter
9
Description
active range of motion
Timepoint
Pre test and post test values of dependent variables are obtained immediately before, immediately, 48 hours, 120 hours and 14 days after the performance of 2 bouts of eccentric exercise
Method of measurement
degree
10
Description
passive range of motion
Timepoint
Pre test and post test values of dependent variables are obtained immediately before, immediately, 48 hours, 120 hours and 14 days after the performance of 2 bouts of eccentric exercise
Method of measurement
degree
11
Description
thigh circumference
Timepoint
Pre test and post test values of dependent variables are obtained immediately before, immediately, 48 hours, 120 hours and 14 days after the performance of 2 bouts of eccentric exercise
Method of measurement
milimeter
Secondary outcomes
empty
Intervention groups
1
Description
control group: performing 2 bouts of knee extensor maximal eccentric exercise (6 set, 20 trial) at 120 degree per second velocity(separated with 2 weeks) in one extremity
Category
Other
2
Description
intervention group: performing 1 bout of knee extensor maximal eccentric exercise (6 set, 20 trial) at 120 degree per second velocity in one extremity and repeat it 2 weeks later in contralateral untrained extremity
Category
Other
Recruitment centers
1
Recruitment center
Name of recruitment center
physical medicine research center in Imam Reza hospital
Full name of responsible person
Dr Salek-Zamani
Street address
Tabriz Golgasht Av. Imam Reza hospital
City
Tabriz
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Dr Ebrahimi
Street address
Tehran Mirdamad Mohseni square School of Rehabilitation
City
Tehran
Grant name
پایان نامه دکتری فیریوتراپی
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Tehran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Dr Ebrahimi
Position
Full Professor of Physiotherapy
Other areas of specialty/work
Street address
Tehran Mirdamad Av. Mohseni square School of Rehabilitation
City
Tehran
Postal code
Phone
+98 21 2222 8051
Fax
Email
ebrahimi.pt@gmail.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
tehran university of medical sciences
Full name of responsible person
mandana rezaei miandoab
Position
Msc of physiotherapy (Phd candidate in tehran university of medical sciences)
Other areas of specialty/work
Street address
tabriz azadi av. before abresan square motahari building unit 105
City
tabriz
Postal code
Phone
+98 41 1337 9268
Fax
Email
m-rezaeim@razi.tums.ac.irmandana.rezae@yahoo.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Mandana Rezaei Miandoab
Position
PhD Candidate of Physiotherapy
Other areas of specialty/work
Street address
Tabriz Azadi Av. before Abresan square Motahari Building 105 Unit