The present investigation are aimed to study the antioxidant activity of Stachys lavandulifolia plant. The trial was conducted on 26 healthy human subjects. They are asked to use 3 g of S. lavandulifolia aerial parts as infusion for 14 days at the morning and evening each day. At the beginning and the end of study, blood samples aretaken from individuals to determine the level of peroxidation of blood lipids as well the total content of serum antioxidants.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2013012210003N2
Registration date:2013-02-06, 1391/11/18
Registration timing:retrospective
Last update:
Update count:0
Registration date
2013-02-06, 1391/11/18
Registrant information
Name
Ali akbar Malekirad
Name of organization / entity
Payame Noor University
Country
Iran (Islamic Republic of)
Phone
+98 86 2422 6073
Email address
malekirad@tabrizu.ac.ir
Recruitment status
Recruitment complete
Funding source
Pharmaceutical Sciences Research Center and Islamic Azad University, Jiroft Branch
Expected recruitment start date
2012-03-19, 1390/12/29
Expected recruitment end date
2013-02-05, 1391/11/17
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The antioxidative activity of Stachys lavandulifolia aqueous extract
Public title
The antioxidative activity of Stachys
Purpose
Prevention
Inclusion/Exclusion criteria
inclusion:age 16-55؛no using any drug؛no exposure to x ray؛ metals؛anesthesia during past year
exclusion:no using regular drug( more than 3 time)؛no tendency to contineus study؛ being menstruation durind study
Age
From 16 years old to 55 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
26
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Not used
Assignment
Single
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Pharmaceutical Sciences Research Center
Street address
Pharmaceutical Sciences Research Center,Faculty of Pharmacy, Theran University of Medical Sciences, 16 Azar Street, Enghelab Street
City
Tehran
Postal code
1417614411
Approval date
2010-08-20, 1389/05/29
Ethics committee reference number
91-11-8:1-1
Health conditions studied
1
Description of health condition studied
Oxidative stress
ICD-10 code
Z00.8
ICD-10 code description
آزمایشات سلامتی در جمعیت مورد مطالعه
Primary outcomes
1
Description
lipid xidationpero
Timepoint
before and after intervention
Method of measurement
thiobarbituric acid method
2
Description
Total Antioxidant Capacity
Timepoint
Before and After intervention
Method of measurement
FRAP method
Secondary outcomes
1
Description
health psychology state
Timepoint
before and after intervention
Method of measurement
General Health Questionare(GHQ)
Intervention groups
1
Description
use 3 g of S. lavandulifolia aerial parts as infusion for 14 days at the morning and evening each day hn healthy subjects
Category
Prevention
Recruitment centers
1
Recruitment center
Name of recruitment center
Persion Gulf Research Center
Full name of responsible person
Ali Akbar Malekirad
Street address
Morghi Avay, Baghe Meli Square, Arak, Iran
City
Arak
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Islamic Azad University, Jiroft Branch
Full name of responsible person
Kavoose Solimani
Street address
Jiroft, Islamic Azad University
City
Jiroft
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Islamic Azad University, Jiroft Branch
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Payame Noor University
Full name of responsible person
Ali Akbar Malekirad
Position
PhD of physiology
Other areas of specialty/work
Street address
Shazand,Arak
City
Shazand
Postal code
Phone
+98 86 2422 6073
Fax
Email
ak_malekirad@yahoo.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
4Faculty of Pharmacy, and Pharmaceutical Sciences Research Center, Tehran University of Medical Scie
Full name of responsible person
Mohammad Abdollahi
Position
PhD of toxicology
Other areas of specialty/work
Street address
4Faculty of Pharmacy, and Pharmaceutical Sciences Research Center, Tehran University of Medical Science, Tehran, Iran
City
Tehran
Postal code
Phone
+98 21 6695 9104
Fax
Email
mohammad@tums.ac.ir
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Payame Noor University
Full name of responsible person
Ali Akbar Malekirad
Position
PhD of physioligy
Other areas of specialty/work
Street address
City
shazand,arak
Postal code
Phone
+86 24226073
Fax
Email
ak_malekirad@yahoo.com
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)