| Revision date | Field name | Previous value |
|---|---|---|
| October 1, 2015 | Expected recruitment end date | 2013-03-18 |
| October 1, 2015 | summary | <br /> The aim of this study will be to investigate the value of intrauterine HCG injection before embryos transfer in improvement of implantation and pregnancy rates in cycles of<br /> IVF/ ICSI. From April 2012 through March 2013 we will evaluated 159 patients undergoing IVF/ICSI at our center for treatment of infertility .<br /> Patients will be divided into three groups using a random numbers table. In all patients in time of monitoring when at least three follicles 18 mm to be seen on ultrasound, 10,000 units HCG will be injected. 36 hours after puncturing oocytes, IVF or ICSI will be performed. Embryo transfer (ET) will be performed48-72 hours after. In the study groups, two groups of injecting HCG intrauterine, Culture media will added to a vial HCG 5000 IU and will be get HCG dilution requirement(1000 unit)for intrauterine injection. In the second or third day after the oocyte pickup ,after inserting a speculum and view the cervix in lithotomy position and after will passed the internal cervical OS, 40 microliter of tissue culture medium containing 1000 IU of hCG through a soft catheter( Cook) will injected intrauterine. Approximately 7minutes after intrauterine HCG injection, between 2-3 embryo through another soft catheter( Cook ) embryo transfer (ET) will be performed. In the control group, ET will performed without the intrauterine hCG injection.In control group between 2-3 embryo through of Cook catheter embryo transfer (ET) will be performed. For luteal phase support progesterone 100 mg intramuscular injection will used .<br /> primary outcomes: Chemical pregnancy, Clinical pregnancy , Implantation rates.<br /> <br /> <br /> |
| October 1, 2015 | summary | <br /> The aim of this study will be to investigate the value of intrauterine HCG injection before embryos transfer in improvement of implantation and pregnancy rates in cycles of<br /> IVF/ ICSI. From April 2012 through March 2013 we will evaluated 159 patients undergoing IVF/ICSI at our center for treatment of infertility .<br /> Patients will be divided into three groups using a random numbers table. In all patients in time of monitoring when at least three follicles 18 mm to be seen on ultrasound, 10,000 units HCG will be injected. 36 hours after puncturing oocytes, IVF or ICSI will be performed. Embryo transfer (ET) will be performed48-72 hours after. In the study groups, two groups of injecting HCG intrauterine, Culture media will added to a vial HCG 5000 IU and will be get HCG dilution requirement(1000 unit)for intrauterine injection. In the second or third day after the oocyte pickup ,after inserting a speculum and view the cervix in lithotomy position and after will passed the internal cervical OS, 40 microliter of tissue culture medium containing 1000 IU of hCG through a soft catheter( Cook) will injected intrauterine. Approximately 7minutes after intrauterine HCG injection, between 2-3 embryo through another soft catheter( Cook ) embryo transfer (ET) will be performed. In the control group, ET will performed without the intrauterine hCG injection.In control group between 2-3 embryo through of Cook catheter embryo transfer (ET) will be performed. For luteal phase support progesterone 100 mg intramuscular injection will used .<br /> primary outcomes: Chemical pregnancy, Clinical pregnancy , Implantation rates.<br /> <br /> <br /> |