The effect of Satureja Hvrtnsz (carvacrol) on the severity of mucositis and pain in children undergoing chemotherapy: a randomized double-blind clinical trial. double-blind clinical trial.

Oral mucositis is a common complication of chemotherapy in children with cancer. Mucositis, resulting in damage to the cells lining the mouth can cause painful inflammation and scarring. Savory Labiatae plants and Pierre traditional medicine as an analgesic and anti-infective effects have been noted. This study aimed to evaluate the efficacy of oral gel on oral ulcer pain and it is savory. The trial was double-blind and in phase two trials is to evaluate the effectiveness of oral gel Savory on 60 children undergoing chemotherapy Who were selected randomly and were divided into two groups of intervention and control groups and allocation was done in parallel. Children with a history of chemotherapy was 3-14 years and in the course of chemotherapy with oral ulcers and, if connecting to the ventilator Shdndantkhab were excluded from the study. In both treatment groups prior to treatment of mucositis continued, the intervention group and the control group Oral gel containing fennel extract 1% placebo gel after detection of oral mucositis twice daily for five days and topical used in the mouth. Since the beginning of the oral daily treatment for five days of lesion severity of oral mucositis using the WHO Ocher pain and pain intensity using a questionnaire recorded and compared results in the two groups that can be based on it is a less costly and less complications used to treat and prevent mucositis.

Vice chancellor for research, Tabriz University of Medical Sciences