Objectives, Compare the differences in clinical testing pain NRS (along with control respiratory rate, heart rate, paradoxical pulse, body temperature, GCS, talking evaluated) before and after the intervention listed from time to time. (2) Design, Clinical trials (3) Setting and conduct, This study was performed double blind. 260 patients referred to Imam Khomeini and Golestan hospitals with biliary colic to be enrolled. First patients to be seen and physical examination are assessed. They will be recorded in the record patients' vital signs and also before any clinical trial resuscitation equipment will be ready. (4) Participants including major eligibility criteria, Inclusion criteria: 1 - MINIMUM AGE 18 and maximum65 years; 2 -Having pain paunch of evaluation by the physician or assistant emergency medicine as biliary colic diagnose; 3 - Unprecedented of stone of the bladder by National rivalries diagnose. exclusion criteria: 1 - Aaged under 18 and Bali 65 years; 2 - The temperature above 38 ºc; 3 - Allergic to ketorolac and other nsaid; 4 -Sensitivity to transdermal fentanyl gasteroentrology; 5 - Patients that tired King outside; 6 - Treatment of anti-making blood in 4 recent weeks; 7 - History ulcers active during 6 recent months; 8 - The history of the disease of blood planning provider; 9 -Patients with safety system, disease of the hepatitis; 10 - Disease of the renal arteries; 11 - Medical problem, acute heart patients; 12 - Pregnant women; 13 - A history of peptic ulcer and pancratit; 14 - Addicts to drugs, mopper foods or any inhalants something; 15 - Failure to confirm biliary colic diagnosed with sonography; 16 -Any problems normal or abnormal in your skin that may attract medicine the skin affected the "having a lot of hair or skin disease; 17 - Receive any kind of pain medication or mopper foods in 8 hours before entering the emergency room (5) Intervention, Injectable ketorolac for intravenous administration of fentanyl skin patch to measure and evaluate pain in patients (6) main outcome measures (variables), Age, gender, temperature, respiratory rate, pulse, blood pressure, pain