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Study aim
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The purpose of this study is to determine the effect of L-arginine with Vitamin C supplementation on Nitrogen balance, Body composition, Vo2max, Growth hormone, Testosterone and Cortisol in male body builders
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Design
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This is a double- blind randomized with control (placebo) clinical trial. The final sample includes 54 athletes who have been selected by convenience sampling method and are placed randomly in two groups of intervention (n=27) and control (n=27) for 6 weeks.
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Settings and conduct
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At The beginning and at the end of the study blood and urine samples are collected and the growth hormone, cortisol, testosterone, Vo2max, nitrogen balance and body composition are compared before and after the intervention
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Participants/Inclusion and exclusion criteria
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Inclusion criteria: tend to participate in the study; male gender;
healthy people; age group between 18-35 years old; Exclusion criteria: Using anabolic drugs, cigarette, alcohol,
any supplement during the study and before the study; cardiovascular diseases, diabetes, hypertension, acute psychiatric disorders, cold, inflammatory diseases, physical injury.
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Intervention groups
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The intervention group will receive daily 3 grams of L-arginine supplement 3 times a day with 500 mg vitamin C once a day for 6 weeks;The control group will receive 3 grams of L-arginine supplement 3 times a day with 500 mg of vitamin C as a placebo ( starch) for 6 weeks.Each 2 groups will have a training protocol for 6 weeks, 3 sessions per week for 1 hour , based on the Cramer and Ratans protocols.
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Main outcome variables
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Nitrogen balance; Body composition; Vo2max; Growth Hormone; Testosterone;Cortisol