Survey of effect of two single doses of bolus Dexmedetomidine (1 µg / kg and 2 µg / kg) on intraoperative hemodynamic status and agitation in the recovery of children undergoing Adenotonsillectomy;

1. Determination and comparison of mean arterial pressure before induction of anesthesia and every 15 minutes during surgery and recovery 2. Determination and comparison of mean heart rate before induction of anesthesia and every 15 minutes during surgery and recovery 3. Determination and comparison of mean SPO2 before induction of anesthesia and every 15 minutes during surgery and recovery 4. Determination and comparison of mean volume of bleeding during surgery based on CC 5. Determine and compare the average length of Intubation 6. Determine and compare the average length of stay in recovery 7. Determine and compare sedation score every 15 minutes 8. Determine and compare agitation score every 15 minutes 9. Determination and comparison of the average dose of propofol for the treatment of delirium

Clinical trial with control group, with 3 parallel groups, double blind, randomized، sample size:105 people

The study is a double-blind randomized clinical trial conducted at Imam Hossein Children's Hospital in 1993-1999.

Inclusion criteria: Children aged 3 to 10 years are candidates for ASAI, ASAII adenotonsillectomy and consent to participate in the study.Exclusion criteria: include any underlying disease , bleeding disorders, impaired coagulation tests and metabolic disorders

three groups of 35 each: The first group received 1 µg / kg diluted dexmedetomidine in a volume of 10 ml slowly for ten minutes and the second group received 2 µg / kg diluted dexmedetomidine in a volume of 10 ml slowly for ten minutes and the third group received 10 ml of normal saline slowly. Within 10 minutes

Blood pressure, bradycardia, respiratory depression, Delirium

First, 105 eligible patients are selected by simple random sampling, then to divide them into three groups, we use Random Allocation software, so that the code selected by this software for three groups of 35 people in 3 envelopes in packages A, B and C Each envelope will be assigned to one of the three groups by the person who is not involved in the process. For example, envelope A, which contains 35 random codes from 1001 to 1105, will be randomly assigned to one of the three intervention groups 1, or intervention 2, or control, and the syringes will be prepared according to the blinding conditions.

To meet the double blindness of the study, doses of both micrograms per kg and one micrograms per kg diluted Dexmedetomidine in a volume of 10 cc are embedded in the syringes. The other syringe will be made without dexmedetomidine and contains only 10 cc Normal saline. The specialist in these syringes will label the A, B and C labels and will provide the researcher daily. Thus, until the data is collected by the nurse, the registrant will not know the type of medication in the syringes. the information analyst will have no knowledge of the types of groups.

If necessary, the data can be published without name and with all the details.

6 months after printing the results.

Researchers working in popular scientific and academic centers who are employed and studying and have a relevant research in this field that needs my data to advance research.

If the data of this study is needed to progress and conduct a similar study.

The original authors of the study.

The researcher emails a valid letter from his / her work or employment stating the reason for the need for the data and after reviewing it in the research department and after the agreement of the authors and financial support centers, the data and documents are provided to them.