Protocol summary

Study aim
To compare the effects of Same Arm Movement Therapy (SAME) Vs Constraint Induced Movement Therapy (CIMT) to improve upper-limb function in chronic Stroke.
Design
Randomized clinical trial.
Settings and conduct
Riphah Rehabilitation Center, Spine & Physiotherapy Rehab Centre
Participants/Inclusion and exclusion criteria
Inclusion Criteria: Confirmed infract or Hemorrhage by a neurologist using either MRI or CT scan. Age between 30-65. History of stroke 1–6 months prior to participation in the project. Patients who provided consents to participate in the study. Proper balance and safety while wearing the restraint Exclusion Criteria: Patients were not considered for participation in the trial if: They were discharged from hospital within 1 week. Patients with implants such as Neuro stimulator containing electric circurity and implants generating electric sign. Patients with anxiety and claustrophobia with diagnosed psychological disorder. Patients undergoing chemotherapy. Alcohol dependency or evidence of substance abuse. Patients without any visual-perceptual problems. Patients without any communication barriers/language issue. Patients with no significant cognitive impairments
Intervention groups
Group A: SAME Therapy treatment protocol consists of 8 weeks of mental rehearsal of upper limb movements during 45-min supervised sessions three times a week and structured independent sessions twice a week. Group B: CIMT treatment protocol consists of 8 weeks of daily intensive training of the affected extremity for 2 hours per day, 5 days per week, and 8 weeks in association with restriction of the non-affected extremity for 10 hours a day.
Main outcome variables
Wolf motor function test, Action Research Arm test

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20200620047848N1
Registration date: 2020-10-01, 1399/07/10
Registration timing: registered_while_recruiting

Last update: 2020-10-01, 1399/07/10
Update count: 0
Registration date
2020-10-01, 1399/07/10
Registrant information
Name
Alina Shaukat
Name of organization / entity
Riphah College of Rehabilitation & Allied Health Sciences
Country
Pakistan
Phone
+92 42 36610923
Email address
alinashaukat07@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2020-09-08, 1399/06/18
Expected recruitment end date
2020-11-08, 1399/08/18
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of effects of Same Arm Movement Therapy (SAME) Vs Constraint Induced Movement Therapy (CIMT) to improve upper-limb function in chronic Stroke
Public title
Comparison of effects of Same Arm Movement Therapy (SAME) Vs Constraint Induced Movement Therapy (CIMT) to improve upper-limb function in chronic Stroke
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Confirmed infarct or Hemorrhage by a neurologist using either MRI or CT scan Age between 30-65 History of stroke 1–6 months prior to participation in the project Patients who provided consents to participate in the study Proper balance and safety while wearing the restraint
Exclusion criteria:
They were discharged from hospital within 1 week Patients participating in any experimental rehabilitation on drug studies Patients with implants such as Neuro stimulator containing electric circurity and implants generating electric sign Patients with anxiety and claustrophobia with diagnosed psychological disorder Patients undergoing chemotherapy Alcohol dependency or evidence of substance abuse Patients without any visual-perceptual problems Patients without any communication barriers/language issue Patients with no significant cognitive impairments
Age
From 30 years old to 65 years old
Gender
Both
Phase
2
Groups that have been masked
  • Participant
Sample size
Target sample size: 22
Randomization (investigator's opinion)
Randomized
Randomization description
Randomization by lottery method. Allocation concealment through sealed envelope
Blinding (investigator's opinion)
Single blinded
Blinding description
participant will be blinded
Placebo
Not used
Assignment
Parallel
Other design features
Non- Probability Convenient Sampling will be used to recruit the individuals for the study and then randomization will be done by lottery method to divide the individuals into 2 treatment groups. Sealed envelope will be used for allocation concealment.

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Riphah College of Rehabilitation & Allied health Sciences
Street address
Madar-e-Millat Road, Quaid-e-Azam Industrial Estate
City
Lahore
Postal code
54770
Approval date
2020-01-01, 1398/10/11
Ethics committee reference number
RCRS-RE-MS-NMPT/FALL 19/026

Health conditions studied

1

Description of health condition studied
Chronic stroke
ICD-10 code
ICD-10 code description

Primary outcomes

1

Description
upper limb strength
Timepoint
Total 8 week program and No followup. Primary outcome will be measured on 8th week.
Method of measurement
Wolf motor function test, Action Research Arm Test

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group A: SAME Therapy treatment protocols consist of 8 weeks of mental rehearsals of upper limb movements during 45-mints supervised sessions three times a week and structural independent sessions twice a week.
Category
Rehabilitation

2

Description
Intervention group B: CIMT treatment protocol consists of 8 weeks of daily intensive training of the affected extremity for 2 hours per day, 5 days per week, and 8 weeks in association with restriction of the non-affected extremity for 10 hours a day.
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
Riphah Rehabilitation Center, Lahore
Full name of responsible person
Alina Shaukat
Street address
28 Madar-e-Millat Road, Quaid-e-Azam Industrial Estate Quaid e Azam Industrial Estate, Lahore, Punjab 54760
City
Lahore
Postal code
54760
Phone
+92 42 32172454
Email
alinashaukat07@gmail.com
Web page address

2

Recruitment center
Name of recruitment center
Spine & Physiotherapy Rehab Centre
Full name of responsible person
Alina Shaukat
Street address
Al Fazal Hospital, 9-B, Board of Revenue Housing Society Johar Town, Lahore, Punjab 54000
City
Lahore
Postal code
54760
Phone
+92 42 32172454
Email
alinashaukat07@gmail.com
Web page address

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Ripah International University
Full name of responsible person
Alina Shaukat
Street address
Madar-e-Millat Road, Quaid-e-Azam Industrial Estae
City
Lahore
Postal code
54770
Phone
+92 42 32172454
Email
alinashaukat07@gmail.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Ripah International University
Proportion provided by this source
100
Public or private sector
Private
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Other

Person responsible for general inquiries

Contact
Name of organization / entity
Ripah International University
Full name of responsible person
Alina Shaukat
Position
Student
Latest degree
Master
Other areas of specialty/work
Physiotherapy
Street address
Madar-e-Millat Road, Quaid-e-Azam Industrial Estate
City
Lahore
Province
Punjab
Postal code
54770
Phone
0432172454
Email
alinashaukat07@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Ripah International University
Full name of responsible person
Alina Shaukat
Position
Student
Latest degree
Master
Other areas of specialty/work
Physiotherapy
Street address
Madar-e-Millat Road, Quaid-e-Azam Industrial Estate
City
Lahore
Province
Punjab
Postal code
54770
Phone
+92 42 32172454
Email
alinashaukat07@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Ripah International University
Full name of responsible person
Alina Shaukat
Position
Student
Latest degree
Master
Other areas of specialty/work
Physiotherapy
Street address
Madar-e-Millat Road, Quaid-e-Azam Industrial Estate.
City
Lahore
Province
Punjab
Postal code
54770
Phone
+92 42 32172454
Email
alinashaukat07@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
No - There is not a plan to make this available
Justification/reason for indecision/not sharing IPD
there is no further decision and information decided yet
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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